Cargando…
The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and di...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599153/ https://www.ncbi.nlm.nih.gov/pubmed/34803717 http://dx.doi.org/10.3389/fphar.2021.775034 |
_version_ | 1784600884742717440 |
---|---|
author | Nowak, Anna Kojder, Klaudyna Zielonka-Brzezicka, Joanna Wróbel, Jacek Bosiacki, Mateusz Fabiańska, Marta Wróbel, Mariola Sołek-Pastuszka, Joanna Klimowicz, Adam |
author_facet | Nowak, Anna Kojder, Klaudyna Zielonka-Brzezicka, Joanna Wróbel, Jacek Bosiacki, Mateusz Fabiańska, Marta Wróbel, Mariola Sołek-Pastuszka, Joanna Klimowicz, Adam |
author_sort | Nowak, Anna |
collection | PubMed |
description | Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and disorientation, which occurs as a result of the loss of neuronal structure and function in different brain areas. In recent years, more and more attention has been paid to use in the treatment of natural bioactive compounds that will be effective in neurodegenerative diseases, including Alzheimer’s disease. G. biloba L. and its most frequently used standardized extract (EGb 761), have been used for many years in supportive therapy and in the prevention of cognitive disorders. The paper presents an overview of reports on the pathogenesis of Alzheimer’s disease, as well as a summary of the properties of G. biloba extract and its effects on the possible pathogenesis of the disease. By exploring more about the pathogenesis of the disease and the benefits of G. biloba extract for patients with Alzheimer’s disease, it will be possible to create an individualized therapeutic protocol to optimize the treatment. |
format | Online Article Text |
id | pubmed-8599153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85991532021-11-19 The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease Nowak, Anna Kojder, Klaudyna Zielonka-Brzezicka, Joanna Wróbel, Jacek Bosiacki, Mateusz Fabiańska, Marta Wróbel, Mariola Sołek-Pastuszka, Joanna Klimowicz, Adam Front Pharmacol Pharmacology Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and disorientation, which occurs as a result of the loss of neuronal structure and function in different brain areas. In recent years, more and more attention has been paid to use in the treatment of natural bioactive compounds that will be effective in neurodegenerative diseases, including Alzheimer’s disease. G. biloba L. and its most frequently used standardized extract (EGb 761), have been used for many years in supportive therapy and in the prevention of cognitive disorders. The paper presents an overview of reports on the pathogenesis of Alzheimer’s disease, as well as a summary of the properties of G. biloba extract and its effects on the possible pathogenesis of the disease. By exploring more about the pathogenesis of the disease and the benefits of G. biloba extract for patients with Alzheimer’s disease, it will be possible to create an individualized therapeutic protocol to optimize the treatment. Frontiers Media S.A. 2021-11-04 /pmc/articles/PMC8599153/ /pubmed/34803717 http://dx.doi.org/10.3389/fphar.2021.775034 Text en Copyright © 2021 Nowak, Kojder, Zielonka-Brzezicka, Wróbel, Bosiacki, Fabiańska, Wróbel, Sołek-Pastuszka and Klimowicz. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Nowak, Anna Kojder, Klaudyna Zielonka-Brzezicka, Joanna Wróbel, Jacek Bosiacki, Mateusz Fabiańska, Marta Wróbel, Mariola Sołek-Pastuszka, Joanna Klimowicz, Adam The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease |
title | The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease |
title_full | The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease |
title_fullStr | The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease |
title_full_unstemmed | The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease |
title_short | The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease |
title_sort | use of ginkgo biloba l. as a neuroprotective agent in the alzheimer’s disease |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599153/ https://www.ncbi.nlm.nih.gov/pubmed/34803717 http://dx.doi.org/10.3389/fphar.2021.775034 |
work_keys_str_mv | AT nowakanna theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT kojderklaudyna theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT zielonkabrzezickajoanna theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT wrobeljacek theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT bosiackimateusz theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT fabianskamarta theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT wrobelmariola theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT sołekpastuszkajoanna theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT klimowiczadam theuseofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT nowakanna useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT kojderklaudyna useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT zielonkabrzezickajoanna useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT wrobeljacek useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT bosiackimateusz useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT fabianskamarta useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT wrobelmariola useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT sołekpastuszkajoanna useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease AT klimowiczadam useofginkgobilobalasaneuroprotectiveagentinthealzheimersdisease |