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The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease

Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and di...

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Autores principales: Nowak, Anna, Kojder, Klaudyna, Zielonka-Brzezicka, Joanna, Wróbel, Jacek, Bosiacki, Mateusz, Fabiańska, Marta, Wróbel, Mariola, Sołek-Pastuszka, Joanna, Klimowicz, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599153/
https://www.ncbi.nlm.nih.gov/pubmed/34803717
http://dx.doi.org/10.3389/fphar.2021.775034
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author Nowak, Anna
Kojder, Klaudyna
Zielonka-Brzezicka, Joanna
Wróbel, Jacek
Bosiacki, Mateusz
Fabiańska, Marta
Wróbel, Mariola
Sołek-Pastuszka, Joanna
Klimowicz, Adam
author_facet Nowak, Anna
Kojder, Klaudyna
Zielonka-Brzezicka, Joanna
Wróbel, Jacek
Bosiacki, Mateusz
Fabiańska, Marta
Wróbel, Mariola
Sołek-Pastuszka, Joanna
Klimowicz, Adam
author_sort Nowak, Anna
collection PubMed
description Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and disorientation, which occurs as a result of the loss of neuronal structure and function in different brain areas. In recent years, more and more attention has been paid to use in the treatment of natural bioactive compounds that will be effective in neurodegenerative diseases, including Alzheimer’s disease. G. biloba L. and its most frequently used standardized extract (EGb 761), have been used for many years in supportive therapy and in the prevention of cognitive disorders. The paper presents an overview of reports on the pathogenesis of Alzheimer’s disease, as well as a summary of the properties of G. biloba extract and its effects on the possible pathogenesis of the disease. By exploring more about the pathogenesis of the disease and the benefits of G. biloba extract for patients with Alzheimer’s disease, it will be possible to create an individualized therapeutic protocol to optimize the treatment.
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spelling pubmed-85991532021-11-19 The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease Nowak, Anna Kojder, Klaudyna Zielonka-Brzezicka, Joanna Wróbel, Jacek Bosiacki, Mateusz Fabiańska, Marta Wróbel, Mariola Sołek-Pastuszka, Joanna Klimowicz, Adam Front Pharmacol Pharmacology Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and disorientation, which occurs as a result of the loss of neuronal structure and function in different brain areas. In recent years, more and more attention has been paid to use in the treatment of natural bioactive compounds that will be effective in neurodegenerative diseases, including Alzheimer’s disease. G. biloba L. and its most frequently used standardized extract (EGb 761), have been used for many years in supportive therapy and in the prevention of cognitive disorders. The paper presents an overview of reports on the pathogenesis of Alzheimer’s disease, as well as a summary of the properties of G. biloba extract and its effects on the possible pathogenesis of the disease. By exploring more about the pathogenesis of the disease and the benefits of G. biloba extract for patients with Alzheimer’s disease, it will be possible to create an individualized therapeutic protocol to optimize the treatment. Frontiers Media S.A. 2021-11-04 /pmc/articles/PMC8599153/ /pubmed/34803717 http://dx.doi.org/10.3389/fphar.2021.775034 Text en Copyright © 2021 Nowak, Kojder, Zielonka-Brzezicka, Wróbel, Bosiacki, Fabiańska, Wróbel, Sołek-Pastuszka and Klimowicz. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Nowak, Anna
Kojder, Klaudyna
Zielonka-Brzezicka, Joanna
Wróbel, Jacek
Bosiacki, Mateusz
Fabiańska, Marta
Wróbel, Mariola
Sołek-Pastuszka, Joanna
Klimowicz, Adam
The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_full The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_fullStr The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_full_unstemmed The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_short The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
title_sort use of ginkgo biloba l. as a neuroprotective agent in the alzheimer’s disease
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599153/
https://www.ncbi.nlm.nih.gov/pubmed/34803717
http://dx.doi.org/10.3389/fphar.2021.775034
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