FTLD Patient–Derived Fibroblasts Show Defective Mitochondrial Function and Accumulation of p62

Frontotemporal lobar degeneration (FTLD) is a clinically, genetically, and neuropathologically heterogeneous group of neurodegenerative syndromes, leading to progressive cognitive dysfunction and frontal and temporal atrophy. C9orf72 hexanucleotide repeat expansion (C9-HRE) is the most common geneti...

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Detalles Bibliográficos
Autores principales: Leskelä, Stina, Hoffmann, Dorit, Rostalski, Hannah, Huber, Nadine, Wittrahm, Rebekka, Hartikainen, Päivi, Korhonen, Ville, Leinonen, Ville, Hiltunen, Mikko, Solje, Eino, Remes, Anne M., Haapasalo, Annakaisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599259/
https://www.ncbi.nlm.nih.gov/pubmed/34328616
http://dx.doi.org/10.1007/s12035-021-02475-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599259/
https://www.ncbi.nlm.nih.gov/pubmed/34328616
http://dx.doi.org/10.1007/s12035-021-02475-x

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