Cargando…
New hPSC SOX9 and INS Reporter Cell Lines Facilitate the Observation and Optimization of Differentiation into Insulin-Producing Cells
Differentiation of human pluripotent stem cells into insulin-producing stem cell-derived beta cells harbors great potential for research and therapy of diabetes. SOX9 plays a crucial role during development of the pancreas and particularly in the development of insulin-producing cells as SOX9(+) cel...
Autores principales: | Dettmer, Rabea, Niwolik, Isabell, Mehmeti, Ilir, Jörns, Anne, Naujok, Ortwin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599335/ https://www.ncbi.nlm.nih.gov/pubmed/34415483 http://dx.doi.org/10.1007/s12015-021-10232-9 |
Ejemplares similares
-
Proinflammatory cytokines induce rapid, NO-independent apoptosis, expression of chemotactic mediators and interleukin-32 secretion in human pluripotent stem cell-derived beta cells
por: Dettmer, Rabea, et al.
Publicado: (2022) -
Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential
por: Sahabian, Anais, et al.
Publicado: (2019) -
Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture
por: Diekmann, Ulf, et al.
Publicado: (2019) -
FGF2 Inhibits Early Pancreatic Lineage Specification during Differentiation of Human Embryonic Stem Cells
por: Dettmer, Rabea, et al.
Publicado: (2020) -
Perspectives on the cost of goods for hPSC banks for manufacture of cell therapies
por: Kim, Jung-Hyun, et al.
Publicado: (2022)