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New hPSC SOX9 and INS Reporter Cell Lines Facilitate the Observation and Optimization of Differentiation into Insulin-Producing Cells

Differentiation of human pluripotent stem cells into insulin-producing stem cell-derived beta cells harbors great potential for research and therapy of diabetes. SOX9 plays a crucial role during development of the pancreas and particularly in the development of insulin-producing cells as SOX9(+) cel...

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Detalles Bibliográficos
Autores principales: Dettmer, Rabea, Niwolik, Isabell, Mehmeti, Ilir, Jörns, Anne, Naujok, Ortwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599335/
https://www.ncbi.nlm.nih.gov/pubmed/34415483
http://dx.doi.org/10.1007/s12015-021-10232-9

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