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Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia

Leishmania major and Leishmania tropica cause cutaneous leishmaniasis in humans and dogs in several parts of the world, with a large number of cases recorded in the Middle East. However, when they occur in sympatry, the role of each species of Leishmania in the epidemiology of cutaneous leishmaniasi...

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Autores principales: Alanazi, Abdullah D., Alouffi, Abdulazi S., Alyousif, Mohamed S., Rahi, Abdulsadah A., Ali, Magda A., Abdullah, Hend H. A. M., Brayner, Fabio A., Mendoza-Roldan, Jairo Alfonso, Bezerra-Santos, Marcos Antonio, Otranto, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599340/
https://www.ncbi.nlm.nih.gov/pubmed/33945011
http://dx.doi.org/10.1007/s00436-021-07166-z
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author Alanazi, Abdullah D.
Alouffi, Abdulazi S.
Alyousif, Mohamed S.
Rahi, Abdulsadah A.
Ali, Magda A.
Abdullah, Hend H. A. M.
Brayner, Fabio A.
Mendoza-Roldan, Jairo Alfonso
Bezerra-Santos, Marcos Antonio
Otranto, Domenico
author_facet Alanazi, Abdullah D.
Alouffi, Abdulazi S.
Alyousif, Mohamed S.
Rahi, Abdulsadah A.
Ali, Magda A.
Abdullah, Hend H. A. M.
Brayner, Fabio A.
Mendoza-Roldan, Jairo Alfonso
Bezerra-Santos, Marcos Antonio
Otranto, Domenico
author_sort Alanazi, Abdullah D.
collection PubMed
description Leishmania major and Leishmania tropica cause cutaneous leishmaniasis in humans and dogs in several parts of the world, with a large number of cases recorded in the Middle East. However, when they occur in sympatry, the role of each species of Leishmania in the epidemiology of cutaneous leishmaniasis (CL) is not clear. To assess the frequency and to identify the species of Leishmania that infect humans and stray dogs in Riyadh and Al-Qaseem (Saudi Arabia), 311 stray dogs and 27 human patients who were suspected for Leishmania infection were examined for CL by a nested polymerase chain reaction (nPCR). Seven (25.9%) out of 27 human patients scored positive for Leishmania spp. (i.e., L. major in five patients from Riyadh and L. tropica in two patients from Al-Qaseem). Out of 311 dogs, five (1.6%) were infected by L. tropica. Data herein presented demonstrate the occurrence of L. tropica in dogs and humans in Saudi Arabia, as well as the occurrence of L. major in humans.
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spelling pubmed-85993402021-11-24 Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia Alanazi, Abdullah D. Alouffi, Abdulazi S. Alyousif, Mohamed S. Rahi, Abdulsadah A. Ali, Magda A. Abdullah, Hend H. A. M. Brayner, Fabio A. Mendoza-Roldan, Jairo Alfonso Bezerra-Santos, Marcos Antonio Otranto, Domenico Parasitol Res Protozoology - Original Paper Leishmania major and Leishmania tropica cause cutaneous leishmaniasis in humans and dogs in several parts of the world, with a large number of cases recorded in the Middle East. However, when they occur in sympatry, the role of each species of Leishmania in the epidemiology of cutaneous leishmaniasis (CL) is not clear. To assess the frequency and to identify the species of Leishmania that infect humans and stray dogs in Riyadh and Al-Qaseem (Saudi Arabia), 311 stray dogs and 27 human patients who were suspected for Leishmania infection were examined for CL by a nested polymerase chain reaction (nPCR). Seven (25.9%) out of 27 human patients scored positive for Leishmania spp. (i.e., L. major in five patients from Riyadh and L. tropica in two patients from Al-Qaseem). Out of 311 dogs, five (1.6%) were infected by L. tropica. Data herein presented demonstrate the occurrence of L. tropica in dogs and humans in Saudi Arabia, as well as the occurrence of L. major in humans. Springer Berlin Heidelberg 2021-05-04 2021 /pmc/articles/PMC8599340/ /pubmed/33945011 http://dx.doi.org/10.1007/s00436-021-07166-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Protozoology - Original Paper
Alanazi, Abdullah D.
Alouffi, Abdulazi S.
Alyousif, Mohamed S.
Rahi, Abdulsadah A.
Ali, Magda A.
Abdullah, Hend H. A. M.
Brayner, Fabio A.
Mendoza-Roldan, Jairo Alfonso
Bezerra-Santos, Marcos Antonio
Otranto, Domenico
Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia
title Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia
title_full Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia
title_fullStr Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia
title_full_unstemmed Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia
title_short Molecular characterization of Leishmania species from stray dogs and human patients in Saudi Arabia
title_sort molecular characterization of leishmania species from stray dogs and human patients in saudi arabia
topic Protozoology - Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599340/
https://www.ncbi.nlm.nih.gov/pubmed/33945011
http://dx.doi.org/10.1007/s00436-021-07166-z
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