Tumor cell PD-L1 expression is a strong predictor of unfavorable prognosis in immune checkpoint therapy-naive clear cell renal cell cancer

BACKGROUND: PD-L1 expression predicts response to immune checkpoint inhibitors in renal cell carcinomas (RCC), but has also been suggested to be linked to poor patient outcome. METHODS: We analyzed PD-L1 in > 1400 RCC in a tissue microarray format by immunohistochemistry. Results were compared wi...

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Detalles Bibliográficos
Autores principales: Möller, Katharina, Fraune, Christoph, Blessin, Niclas C., Lennartz, Maximilian, Kluth, Martina, Hube-Magg, Claudia, Lindhorst, Linnea, Dahlem, Roland, Fisch, Margit, Eichenauer, Till, Riechardt, Silke, Simon, Ronald, Sauter, Guido, Büscheck, Franziska, Höppner, Wolfgang, Matthies, Cord, Doh, Ousman, Krech, Till, Marx, Andreas H., Zecha, Henrik, Rink, Michael, Steurer, Stefan, Clauditz, Till S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
UROLOGY - Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599390/
https://www.ncbi.nlm.nih.gov/pubmed/33797012
http://dx.doi.org/10.1007/s11255-021-02841-7

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