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TRAIL/DR5 pathway promotes AKT phosphorylation, skeletal muscle differentiation, and glucose uptake
TNF-related apoptosis-inducing ligand (TRAIL) is a protein that induces apoptosis in cancer cells but not in normal ones, where its effects remain to be fully understood. Previous studies have shown that in high-fat diet (HFD)-fed mice, TRAIL treatment reduced body weight gain, insulin resistance, a...
Autores principales: | Toffoli, Barbara, Tonon, Federica, Tisato, Veronica, Zauli, Giorgio, Secchiero, Paola, Fabris, Bruno, Bernardi, Stella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599458/ https://www.ncbi.nlm.nih.gov/pubmed/34789726 http://dx.doi.org/10.1038/s41419-021-04383-3 |
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