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Non-equilibrium phase transition at a critical point of human blood
Blood is the basic medium in the existence, evolution and physiological balance of animals and represents the biochemical “Internet” of the body; at least human blood exhibit the presence of an emergent phase that is highly unusual. Homeostasis, the state of the optimal functioning of the body, is m...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599461/ https://www.ncbi.nlm.nih.gov/pubmed/34789814 http://dx.doi.org/10.1038/s41598-021-01909-9 |
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author | Pietruszka, Mariusz A. |
author_facet | Pietruszka, Mariusz A. |
author_sort | Pietruszka, Mariusz A. |
collection | PubMed |
description | Blood is the basic medium in the existence, evolution and physiological balance of animals and represents the biochemical “Internet” of the body; at least human blood exhibit the presence of an emergent phase that is highly unusual. Homeostasis, the state of the optimal functioning of the body, is maintained in living organisms by many chemical and physical conditions, particularly temperature. However, no regulatory mechanism has been identified that has led to a predetermined (molecularly encoded) optimal, individually variable, very specific temperature of around 36 °C. Additionally, the homeostatic temperature range, which is kept within predetermined limits, is merely an empirical fact. In the following, I will show that the reference temperature that is necessary to achieve homeostasis can be established, and a preset homeostatic range can be determined, using an original experimental method and refined tools of mathematical physics related to the nonlinear measures of the complexity of human blood. Moreover, signatures of a macroscopic coherent state in a non-equilibrium system at a critical temperature are obtained. |
format | Online Article Text |
id | pubmed-8599461 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-85994612021-11-19 Non-equilibrium phase transition at a critical point of human blood Pietruszka, Mariusz A. Sci Rep Article Blood is the basic medium in the existence, evolution and physiological balance of animals and represents the biochemical “Internet” of the body; at least human blood exhibit the presence of an emergent phase that is highly unusual. Homeostasis, the state of the optimal functioning of the body, is maintained in living organisms by many chemical and physical conditions, particularly temperature. However, no regulatory mechanism has been identified that has led to a predetermined (molecularly encoded) optimal, individually variable, very specific temperature of around 36 °C. Additionally, the homeostatic temperature range, which is kept within predetermined limits, is merely an empirical fact. In the following, I will show that the reference temperature that is necessary to achieve homeostasis can be established, and a preset homeostatic range can be determined, using an original experimental method and refined tools of mathematical physics related to the nonlinear measures of the complexity of human blood. Moreover, signatures of a macroscopic coherent state in a non-equilibrium system at a critical temperature are obtained. Nature Publishing Group UK 2021-11-17 /pmc/articles/PMC8599461/ /pubmed/34789814 http://dx.doi.org/10.1038/s41598-021-01909-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Pietruszka, Mariusz A. Non-equilibrium phase transition at a critical point of human blood |
title | Non-equilibrium phase transition at a critical point of human blood |
title_full | Non-equilibrium phase transition at a critical point of human blood |
title_fullStr | Non-equilibrium phase transition at a critical point of human blood |
title_full_unstemmed | Non-equilibrium phase transition at a critical point of human blood |
title_short | Non-equilibrium phase transition at a critical point of human blood |
title_sort | non-equilibrium phase transition at a critical point of human blood |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599461/ https://www.ncbi.nlm.nih.gov/pubmed/34789814 http://dx.doi.org/10.1038/s41598-021-01909-9 |
work_keys_str_mv | AT pietruszkamariusza nonequilibriumphasetransitionatacriticalpointofhumanblood |