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P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells

Tumor growth and metastatic spreading are heavily affected by the P2X7 receptor as well as microvesicles and exosomes release into the tumor microenvironment. P2X7 receptor stimulation is known to trigger vesicular release from immune and central nervous system cells. However, P2X7 role in microvesi...

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Detalles Bibliográficos
Autores principales: Pegoraro, Anna, De Marchi, Elena, Ferracin, Manuela, Orioli, Elisa, Zanoni, Michele, Bassi, Cristian, Tesei, Anna, Capece, Marina, Dika, Emi, Negrini, Massimo, Di Virgilio, Francesco, Adinolfi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599616/
https://www.ncbi.nlm.nih.gov/pubmed/34789738
http://dx.doi.org/10.1038/s41419-021-04378-0