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Structural dynamics and determinants of 2-aminoadenine specificity in DNA polymerase DpoZ of vibriophage ϕVC8

All genetic information in cellular life is stored in DNA copolymers composed of four basic building blocks (ATGC-DNA). In contrast, a group of bacteriophages belonging to families Siphoviridae and Podoviridae has abandoned the usage of one of them, adenine (A), replacing it with 2-aminoadenine (Z)....

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Detalles Bibliográficos
Autores principales: Czernecki, Dariusz, Hu, Haidai, Romoli, Filippo, Delarue, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599892/
https://www.ncbi.nlm.nih.gov/pubmed/34751404
http://dx.doi.org/10.1093/nar/gkab955