Cargando…

Impact of Hydrocortisone and of CRH Infusion on the Hypothalamus-Pituitary-Adrenocortical Axis of Septic Male Mice

PURPOSE: Sepsis is hallmarked by high plasma cortisol/corticosterone (CORT), low adrenocorticotropic hormone (ACTH), and high pro-opiomelanocortin (POMC). While corticotropin-releasing hormone-(CRH) and arginine-vasopressin (AVP)-driven pituitary POMC expression remains active, POMC processing into...

Descripción completa

Detalles Bibliográficos
Autores principales:	Téblick, Arno, De Bruyn, Lauren, Van Oudenhove, Tim, Vander Perre, Sarah, Pauwels, Lies, Derde, Sarah, Langouche, Lies, Van den Berghe, Greet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599906/ https://www.ncbi.nlm.nih.gov/pubmed/34698826 http://dx.doi.org/10.1210/endocr/bqab222

Ejemplares similares

The Hypothalamus-pituitary-adrenocortical Response to Critical Illness: A Concept in Need of Revision
por: Langouche, Lies, et al.
Publicado: (2023)

The role of pro-opiomelanocortin in the ACTH–cortisol dissociation of sepsis
por: Téblick, Arno, et al.
Publicado: (2021)

OR19-06 Sepsis-Induced Critical Illness in Mice Alters Key Regulators of ACTH Production and Secretion Within the Anterior Pituitary Gland
por: Téblick, Arno, et al.
Publicado: (2020)

The hypothalamus-pituitary-adrenal axis in sepsis- and hyperinflammation-induced critical illness: Gaps in current knowledge and future translational research directions
por: Van den Berghe, Greet, et al.
Publicado: (2022)

Anterior pituitary function in critical illness
por: Téblick, Arno, et al.
Publicado: (2019)

Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness
por: Weckx, Ruben, et al.
Publicado: (2022)

OR20-6 Ketones and Sepsis-Induced Muscle Weakness: Signal or Fuel for Protection?
por: Weckx, Ruben, et al.
Publicado: (2019)

Obesity attenuates inflammation, protein catabolism, dyslipidaemia, and muscle weakness during sepsis, independent of leptin
por: Vankrunkelsven, Wouter, et al.
Publicado: (2022)

Identification of the toxic threshold of 3-hydroxybutyrate-sodium supplementation in septic mice
por: Weckx, Ruben, et al.
Publicado: (2021)

ACTH and cortisol responses to CRH in acute, subacute, and prolonged critical illness: a randomized, double-blind, placebo-controlled, crossover cohort study
por: Peeters, Bram, et al.
Publicado: (2018)

OR26-4 Glucocorticoid Receptor Expression and Signaling During Critical Illness, in Relation to the Duration of Illness and the Systemic Glucocorticoid Availability: A Prospective, Observational, Cross-Sectional Human and a Translational Mouse Study
por: Téblick, Arno, et al.
Publicado: (2022)

Adipose tissue protects against sepsis-induced muscle weakness in mice: from lipolysis to ketones
por: Goossens, Chloë, et al.
Publicado: (2019)

SUN-548 Ketone Bodies in Critical Illness Alter Cholesterol Synthesis in Skeletal Muscle, Interlinked with Protection Against Weakness
por: Goossens, Chloë, et al.
Publicado: (2020)

Changes in the central component of the hypothalamus-pituitary-thyroid axis in a rabbit model of prolonged critical illness
por: Mebis, Liese, et al.
Publicado: (2009)

Impact of withholding early parenteral nutrition in adult critically ill patients on ketogenesis in relation to outcome
por: De Bruyn, Astrid, et al.
Publicado: (2021)

Proliferation and differentiation of adipose tissue in prolonged lean and obese critically ill patients
por: Goossens, Chloë, et al.
Publicado: (2017)

Impact of duration of critical illness and level of systemic glucocorticoid availability on tissue-specific glucocorticoid receptor expression and actions: A prospective, observational, cross-sectional human and two translational mouse studies
por: Téblick, Arno, et al.
Publicado: (2022)

Adrenocortical function during prolonged critical illness and beyond: a prospective observational study
por: Peeters, Bram, et al.
Publicado: (2018)

Critical illness induces alternative activation of M2 macrophages in adipose tissue
por: Langouche, Lies, et al.
Publicado: (2011)

Critical illness induces nutrient-independent adipogenesis and accumulation of alternatively activated tissue macrophages
por: Marques, Mirna Bastos, et al.
Publicado: (2013)

Impact of tight glucose control on circulating 3-hydroxybutyrate in critically ill patients
por: Gunst, Jan, et al.
Publicado: (2021)

Altered cholesterol homeostasis in critical illness-induced muscle weakness: effect of exogenous 3-hydroxybutyrate
por: Goossens, Chloë, et al.
Publicado: (2021)

On the Role of Illness Duration and Nutrient Restriction in Cholestatic Alterations that Occur During Critical Illness
por: Jenniskens, Marc, et al.
Publicado: (2018)

Adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin
por: Langouche, Lies, et al.
Publicado: (2009)

Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit
por: De Bruyn, Astrid, et al.
Publicado: (2020)

Premorbid obesity, but not nutrition, prevents critical illness‐induced muscle wasting and weakness
por: Goossens, Chloë, et al.
Publicado: (2016)

Nonthyroidal Illness Syndrome Across the Ages
por: Langouche, Lies, et al.
Publicado: (2019)

Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?
por: Langouche, Lies, et al.
Publicado: (2021)

Skeletal Muscle Myokine Expression in Critical Illness, Association With Outcome and Impact of Therapeutic Interventions
por: Vanhorebeek, Ilse, et al.
Publicado: (2023)

RF09 | PSAT88 Pro-opiomelanocortin (POMC), ACTH and Cortisol Responses to Pediatric Cardiac Surgery
por: Téblick, Arno, et al.
Publicado: (2022)

Dynamics and prognostic value of the hypothalamus–pituitary–adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study
por: Jacobs, An, et al.
Publicado: (2019)

Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model
por: Goossens, Chloë, et al.
Publicado: (2021)

The Role of Autophagy in Critical Illness-induced Liver Damage
por: Thiessen, Steven E., et al.
Publicado: (2017)

Development of muscle weakness in a mouse model of critical illness: does fibroblast growth factor 21 play a role?
por: Vankrunkelsven, Wouter, et al.
Publicado: (2023)

Critical Illness–induced Corticosteroid Insufficiency: What It Is Not and What It Could Be
por: Téblick, Arno, et al.
Publicado: (2022)

OR17-1 Changes in the Hypothalamic-Pituitary-Adrenal Axis during Pediatric Critical Illness
por: Jacobs, An, et al.
Publicado: (2019)

OR26-02 The Effect on Ketogenesis of Withholding Early Parenteral Nutrition in Critically Ill Children, as a Potential Mediator of the Improved Acute Outcome
por: De Bruyn, Astrid, et al.
Publicado: (2020)

Prevalence and Prognostic Value of Abnormal Liver Test Results in Critically Ill Children and the Impact of Delaying Parenteral Nutrition*
por: Jenniskens, Marc, et al.
Publicado: (2018)

SAT-155 Temporal Activation of the Unfolded Protein Response and Concomitant Downregulation of Key Hepatic Transcription Factors in Critical Illness
por: Vankrunkelsven, Wouter, et al.
Publicado: (2019)

Critical illness induces nutrient-independent adipogenesis and accumulation of alternatively activated tissue macrophages
por: Marques, M, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_rm9tm1ogvbu9tim2ahsqe91kuj