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Impact of Hydrocortisone and of CRH Infusion on the Hypothalamus-Pituitary-Adrenocortical Axis of Septic Male Mice

PURPOSE: Sepsis is hallmarked by high plasma cortisol/corticosterone (CORT), low adrenocorticotropic hormone (ACTH), and high pro-opiomelanocortin (POMC). While corticotropin-releasing hormone-(CRH) and arginine-vasopressin (AVP)-driven pituitary POMC expression remains active, POMC processing into...

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Detalles Bibliográficos
Autores principales:	Téblick, Arno, De Bruyn, Lauren, Van Oudenhove, Tim, Vander Perre, Sarah, Pauwels, Lies, Derde, Sarah, Langouche, Lies, Van den Berghe, Greet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599906/ https://www.ncbi.nlm.nih.gov/pubmed/34698826 http://dx.doi.org/10.1210/endocr/bqab222

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