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The lupus autoantigen La/Ssb is an Xist-binding protein involved in Xist folding and cloud formation

Using the programmable RNA-sequence binding domain of the Pumilio protein, we FLAG-tagged Xist (inactivated X chromosome specific transcript) in live mouse cells. Affinity pulldown coupled to mass spectrometry was employed to identify a list of 138 candidate Xist-binding proteins, from which, Ssb (a...

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Detalles Bibliográficos
Autores principales:	Ha, Norbert, Ding, Nan, Hong, Ru, Liu, Rubing, Roca, Xavier, Luo, Yingyuan, Duan, Xiaowei, Wang, Xiao, Ni, Peiling, Wu, Haiyang, Zhang, Li-Feng, Chen, Lingyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599922/ https://www.ncbi.nlm.nih.gov/pubmed/34723322 http://dx.doi.org/10.1093/nar/gkab1003

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