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Context Matters—Why We Need to Change From a One Size Fits all Approach to Made-to-Measure Therapies for Individual Patients With Pancreatic Cancer
Pancreatic cancer is one of the deadliest cancers and remains a major unsolved health problem. While pancreatic ductal adenocarcinoma (PDAC) is associated with driver mutations in only four major genes (KRAS, TP53, SMAD4, and CDKN2A), every tumor differs in its molecular landscape, histology, and pr...
Autores principales: | Sankarasubramanian, Sushmitha, Pfohl, Ulrike, Regenbrecht, Christian R. A., Reinhard, Christoph, Wedeken, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599957/ https://www.ncbi.nlm.nih.gov/pubmed/34805167 http://dx.doi.org/10.3389/fcell.2021.760705 |
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