Cargando…
Exploring the Structures and Functions of Macromolecular SLX4-Nuclease Complexes in Genome Stability
All organisms depend on the ability of cells to accurately duplicate and segregate DNA into progeny. However, DNA is frequently damaged by factors in the environment and from within cells. One of the most dangerous lesions is a DNA double-strand break. Unrepaired breaks are a major driving force for...
Autores principales: | Payliss, Brandon J., Patel, Ayushi, Sheppard, Anneka C., Wyatt, Haley D. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599992/ https://www.ncbi.nlm.nih.gov/pubmed/34804132 http://dx.doi.org/10.3389/fgene.2021.784167 |
Ejemplares similares
-
Protocol for in vitro phosphorylation of the MUS81-binding region of SLX4 using CDK1-cyclin B
por: Payliss, Brandon J., et al.
Publicado: (2023) -
Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex
por: Yin, Jinhu, et al.
Publicado: (2016) -
Recognition and processing of branched DNA substrates by Slx1–Slx4 nuclease
por: Gaur, Vineet, et al.
Publicado: (2019) -
Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease
por: Gaur, Vineet, et al.
Publicado: (2015) -
Nuclease Delivery: Versatile Functions of SLX4/FANCP in Genome Maintenance
por: Kim, Yonghwan
Publicado: (2014)