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Invasive Pathobionts Contribute to Colon Cancer Initiation by Counterbalancing Epithelial Antimicrobial Responses

BACKGROUND & AIMS: Microbiota dysbiosis and mucosa-associated bacteria are involved in colorectal cancer progression. We hypothesize that an interaction between virulent pathobionts and epithelial defense promotes tumorigenesis. METHODS: Chemical-induced CRC mouse model was treated with antibiot...

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Detalles Bibliográficos
Autores principales: Yu, Linda Chia-Hui, Wei, Shu-Chen, Li, Yi-Hsuan, Lin, Po-Yu, Chang, Xin-Yu, Weng, Jui-Ping, Shue, Yin-Wen, Lai, Liang-Chuan, Wang, Jin-Town, Jeng, Yung-Ming, Ni, Yen-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600093/
https://www.ncbi.nlm.nih.gov/pubmed/34418587
http://dx.doi.org/10.1016/j.jcmgh.2021.08.007

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