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Perifosine, a Bioavailable Alkylphospholipid Akt Inhibitor, Exhibits Antitumor Activity in Murine Models of Cancer Brain Metastasis Through Favorable Tumor Exposure

Metastatic brain tumors are regarded as the most advanced stage of certain types of cancer; however, chemotherapy has played a limited role in the treatment of brain metastases. Here, we established murine models of brain metastasis using cell lines derived from human brain metastatic tumors, and ai...

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Detalles Bibliográficos
Autores principales:	Taniguchi, Keisuke, Suzuki, Tomo, Okamura, Tomomi, Kurita, Akinobu, Nohara, Gou, Ishii, Satoru, Kado, Shoichi, Takagi, Akimitsu, Tsugane, Momomi, Shishido, Yoshiyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600181/ https://www.ncbi.nlm.nih.gov/pubmed/34804943 http://dx.doi.org/10.3389/fonc.2021.754365

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