Cargando…
Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies
The development of lateral flow immunoassay (LFIA) using three-dimensional (3D) printing and bioprinting technologies can enhance and accelerate the optimization process of the fabrication. Therefore, the main goal of this study is to investigate methods to speed up the developing process of a LFIA...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Whioce Publishing Pte. Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600310/ https://www.ncbi.nlm.nih.gov/pubmed/34805593 http://dx.doi.org/10.18063/ijb.v7i4.399 |
_version_ | 1784601127537344512 |
---|---|
author | Alrashoudi, Abdulelah A. Albalawi, Hamed I. Aldoukhi, Ali H. Moretti, Manola Bilalis, Panayiotis Abedalthagafi, Malak Hauser, Charlotte A. E. |
author_facet | Alrashoudi, Abdulelah A. Albalawi, Hamed I. Aldoukhi, Ali H. Moretti, Manola Bilalis, Panayiotis Abedalthagafi, Malak Hauser, Charlotte A. E. |
author_sort | Alrashoudi, Abdulelah A. |
collection | PubMed |
description | The development of lateral flow immunoassay (LFIA) using three-dimensional (3D) printing and bioprinting technologies can enhance and accelerate the optimization process of the fabrication. Therefore, the main goal of this study is to investigate methods to speed up the developing process of a LFIA as a tool for community screening. To achieve this goal, an in-house developed robotic arm and microfluidic pumps were used to print the proteins during the development of the test. 3D printing technologies were used to design and print the housing unit for the testing strip. The proposed design was made by taking into consideration the environmental impact of this disposable medical device. |
format | Online Article Text |
id | pubmed-8600310 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Whioce Publishing Pte. Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86003102021-11-18 Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies Alrashoudi, Abdulelah A. Albalawi, Hamed I. Aldoukhi, Ali H. Moretti, Manola Bilalis, Panayiotis Abedalthagafi, Malak Hauser, Charlotte A. E. Int J Bioprint Research Article The development of lateral flow immunoassay (LFIA) using three-dimensional (3D) printing and bioprinting technologies can enhance and accelerate the optimization process of the fabrication. Therefore, the main goal of this study is to investigate methods to speed up the developing process of a LFIA as a tool for community screening. To achieve this goal, an in-house developed robotic arm and microfluidic pumps were used to print the proteins during the development of the test. 3D printing technologies were used to design and print the housing unit for the testing strip. The proposed design was made by taking into consideration the environmental impact of this disposable medical device. Whioce Publishing Pte. Ltd. 2021-08-23 /pmc/articles/PMC8600310/ /pubmed/34805593 http://dx.doi.org/10.18063/ijb.v7i4.399 Text en Copyright: © 2021 Alrashoudi, et al. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Attribution-NonCommercial 4.0 International 4.0 (CC BY-NC 4.0), which permits all non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited. |
spellingShingle | Research Article Alrashoudi, Abdulelah A. Albalawi, Hamed I. Aldoukhi, Ali H. Moretti, Manola Bilalis, Panayiotis Abedalthagafi, Malak Hauser, Charlotte A. E. Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies |
title | Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies |
title_full | Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies |
title_fullStr | Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies |
title_full_unstemmed | Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies |
title_short | Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies |
title_sort | fabrication of a lateral flow assay for rapid in-field detection of covid-19 antibodies using additive manufacturing printing technologies |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600310/ https://www.ncbi.nlm.nih.gov/pubmed/34805593 http://dx.doi.org/10.18063/ijb.v7i4.399 |
work_keys_str_mv | AT alrashoudiabdulelaha fabricationofalateralflowassayforrapidinfielddetectionofcovid19antibodiesusingadditivemanufacturingprintingtechnologies AT albalawihamedi fabricationofalateralflowassayforrapidinfielddetectionofcovid19antibodiesusingadditivemanufacturingprintingtechnologies AT aldoukhialih fabricationofalateralflowassayforrapidinfielddetectionofcovid19antibodiesusingadditivemanufacturingprintingtechnologies AT morettimanola fabricationofalateralflowassayforrapidinfielddetectionofcovid19antibodiesusingadditivemanufacturingprintingtechnologies AT bilalispanayiotis fabricationofalateralflowassayforrapidinfielddetectionofcovid19antibodiesusingadditivemanufacturingprintingtechnologies AT abedalthagafimalak fabricationofalateralflowassayforrapidinfielddetectionofcovid19antibodiesusingadditivemanufacturingprintingtechnologies AT hausercharlotteae fabricationofalateralflowassayforrapidinfielddetectionofcovid19antibodiesusingadditivemanufacturingprintingtechnologies |