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Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies

The development of lateral flow immunoassay (LFIA) using three-dimensional (3D) printing and bioprinting technologies can enhance and accelerate the optimization process of the fabrication. Therefore, the main goal of this study is to investigate methods to speed up the developing process of a LFIA...

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Autores principales: Alrashoudi, Abdulelah A., Albalawi, Hamed I., Aldoukhi, Ali H., Moretti, Manola, Bilalis, Panayiotis, Abedalthagafi, Malak, Hauser, Charlotte A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600310/
https://www.ncbi.nlm.nih.gov/pubmed/34805593
http://dx.doi.org/10.18063/ijb.v7i4.399
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author Alrashoudi, Abdulelah A.
Albalawi, Hamed I.
Aldoukhi, Ali H.
Moretti, Manola
Bilalis, Panayiotis
Abedalthagafi, Malak
Hauser, Charlotte A. E.
author_facet Alrashoudi, Abdulelah A.
Albalawi, Hamed I.
Aldoukhi, Ali H.
Moretti, Manola
Bilalis, Panayiotis
Abedalthagafi, Malak
Hauser, Charlotte A. E.
author_sort Alrashoudi, Abdulelah A.
collection PubMed
description The development of lateral flow immunoassay (LFIA) using three-dimensional (3D) printing and bioprinting technologies can enhance and accelerate the optimization process of the fabrication. Therefore, the main goal of this study is to investigate methods to speed up the developing process of a LFIA as a tool for community screening. To achieve this goal, an in-house developed robotic arm and microfluidic pumps were used to print the proteins during the development of the test. 3D printing technologies were used to design and print the housing unit for the testing strip. The proposed design was made by taking into consideration the environmental impact of this disposable medical device.
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spelling pubmed-86003102021-11-18 Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies Alrashoudi, Abdulelah A. Albalawi, Hamed I. Aldoukhi, Ali H. Moretti, Manola Bilalis, Panayiotis Abedalthagafi, Malak Hauser, Charlotte A. E. Int J Bioprint Research Article The development of lateral flow immunoassay (LFIA) using three-dimensional (3D) printing and bioprinting technologies can enhance and accelerate the optimization process of the fabrication. Therefore, the main goal of this study is to investigate methods to speed up the developing process of a LFIA as a tool for community screening. To achieve this goal, an in-house developed robotic arm and microfluidic pumps were used to print the proteins during the development of the test. 3D printing technologies were used to design and print the housing unit for the testing strip. The proposed design was made by taking into consideration the environmental impact of this disposable medical device. Whioce Publishing Pte. Ltd. 2021-08-23 /pmc/articles/PMC8600310/ /pubmed/34805593 http://dx.doi.org/10.18063/ijb.v7i4.399 Text en Copyright: © 2021 Alrashoudi, et al. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Attribution-NonCommercial 4.0 International 4.0 (CC BY-NC 4.0), which permits all non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited.
spellingShingle Research Article
Alrashoudi, Abdulelah A.
Albalawi, Hamed I.
Aldoukhi, Ali H.
Moretti, Manola
Bilalis, Panayiotis
Abedalthagafi, Malak
Hauser, Charlotte A. E.
Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies
title Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies
title_full Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies
title_fullStr Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies
title_full_unstemmed Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies
title_short Fabrication of a Lateral Flow Assay for Rapid In-Field Detection of COVID-19 Antibodies Using Additive Manufacturing Printing Technologies
title_sort fabrication of a lateral flow assay for rapid in-field detection of covid-19 antibodies using additive manufacturing printing technologies
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600310/
https://www.ncbi.nlm.nih.gov/pubmed/34805593
http://dx.doi.org/10.18063/ijb.v7i4.399
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