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Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance

During normal aging resting-state brain activity changes and working memory performance declines as compared to young adulthood. Interestingly, previous studies reported that different electroencephalographic (EEG) measures of resting-state brain activity may correlate with working memory performanc...

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Autores principales: Jabès, Adeline, Klencklen, Giuliana, Ruggeri, Paolo, Antonietti, Jean-Philippe, Banta Lavenex, Pamela, Lavenex, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600362/
https://www.ncbi.nlm.nih.gov/pubmed/34803651
http://dx.doi.org/10.3389/fnagi.2021.704362
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author Jabès, Adeline
Klencklen, Giuliana
Ruggeri, Paolo
Antonietti, Jean-Philippe
Banta Lavenex, Pamela
Lavenex, Pierre
author_facet Jabès, Adeline
Klencklen, Giuliana
Ruggeri, Paolo
Antonietti, Jean-Philippe
Banta Lavenex, Pamela
Lavenex, Pierre
author_sort Jabès, Adeline
collection PubMed
description During normal aging resting-state brain activity changes and working memory performance declines as compared to young adulthood. Interestingly, previous studies reported that different electroencephalographic (EEG) measures of resting-state brain activity may correlate with working memory performance at different ages. Here, we recorded resting-state EEG activity and tested allocentric spatial working memory in healthy young (20–30 years) and older (65–75 years) adults. We adapted standard EEG methods to record brain activity in mobile participants in a non-shielded environment, in both eyes closed and eyes open conditions. Our study revealed some age-group differences in resting-state brain activity that were consistent with previous results obtained in different recording conditions. We confirmed that age-group differences in resting-state EEG activity depend on the recording conditions and the specific parameters considered. Nevertheless, lower theta-band and alpha-band frequencies and absolute powers, and higher beta-band and gamma-band relative powers were overall observed in healthy older adults, as compared to healthy young adults. In addition, using principal component and regression analyses, we found that the first extracted EEG component, which represented mainly theta, alpha and beta powers, correlated with spatial working memory performance in older adults, but not in young adults. These findings are consistent with the theory that the neurobiological bases of working memory performance may differ between young and older adults. However, individual measures of resting-state EEG activity could not be used as reliable biomarkers to predict individual allocentric spatial working memory performance in young or older adults.
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spelling pubmed-86003622021-11-19 Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance Jabès, Adeline Klencklen, Giuliana Ruggeri, Paolo Antonietti, Jean-Philippe Banta Lavenex, Pamela Lavenex, Pierre Front Aging Neurosci Neuroscience During normal aging resting-state brain activity changes and working memory performance declines as compared to young adulthood. Interestingly, previous studies reported that different electroencephalographic (EEG) measures of resting-state brain activity may correlate with working memory performance at different ages. Here, we recorded resting-state EEG activity and tested allocentric spatial working memory in healthy young (20–30 years) and older (65–75 years) adults. We adapted standard EEG methods to record brain activity in mobile participants in a non-shielded environment, in both eyes closed and eyes open conditions. Our study revealed some age-group differences in resting-state brain activity that were consistent with previous results obtained in different recording conditions. We confirmed that age-group differences in resting-state EEG activity depend on the recording conditions and the specific parameters considered. Nevertheless, lower theta-band and alpha-band frequencies and absolute powers, and higher beta-band and gamma-band relative powers were overall observed in healthy older adults, as compared to healthy young adults. In addition, using principal component and regression analyses, we found that the first extracted EEG component, which represented mainly theta, alpha and beta powers, correlated with spatial working memory performance in older adults, but not in young adults. These findings are consistent with the theory that the neurobiological bases of working memory performance may differ between young and older adults. However, individual measures of resting-state EEG activity could not be used as reliable biomarkers to predict individual allocentric spatial working memory performance in young or older adults. Frontiers Media S.A. 2021-11-04 /pmc/articles/PMC8600362/ /pubmed/34803651 http://dx.doi.org/10.3389/fnagi.2021.704362 Text en Copyright © 2021 Jabès, Klencklen, Ruggeri, Antonietti, Banta Lavenex and Lavenex. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Jabès, Adeline
Klencklen, Giuliana
Ruggeri, Paolo
Antonietti, Jean-Philippe
Banta Lavenex, Pamela
Lavenex, Pierre
Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance
title Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance
title_full Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance
title_fullStr Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance
title_full_unstemmed Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance
title_short Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance
title_sort age-related differences in resting-state eeg and allocentric spatial working memory performance
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600362/
https://www.ncbi.nlm.nih.gov/pubmed/34803651
http://dx.doi.org/10.3389/fnagi.2021.704362
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