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Glucose transporter-1 inhibition overcomes imatinib resistance in gastrointestinal stromal tumor cells
Imatinib mesylate (imatinib) is the primary agent of choice used to treat gastrointestinal stromal tumors (GIST). However, drug resistance to imatinib poses a major obstacle to treatment efficacy. In addition, the relationship between imatinib resistance and glycolysis is poorly understood. Glucose...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600406/ https://www.ncbi.nlm.nih.gov/pubmed/34738628 http://dx.doi.org/10.3892/or.2021.8218 |