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JAK2/STAT3-mediated dose-dependent cytostatic and cytotoxic effects of sesquiterpene lactones from Gymnanthemum extensum on A549 human lung carcinoma cells

Due to drug resistance and disease recurrence, lung cancer remains one of the primary cancer-related causes of death in both men and women worldwide. In addition, lung cancer is clinically silent and thus most patients are at an advanced stage at the time of diagnosis. The limited efficiency of curr...

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Detalles Bibliográficos
Autores principales: Keeratichamroen, Siriporn, Lirdprapamongkol, Kriengsak, Thongnest, Sanit, Boonsombat, Jutatip, Chawengrum, Pornsuda, Sornprachum, Thiwaree, Sirirak, Jitnapa, Verathamjamras, Chris, Ornnork, Narittira, Ruchirawat, Somsak, Svasti, Jisnuson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600427/
https://www.ncbi.nlm.nih.gov/pubmed/34738622
http://dx.doi.org/10.3892/or.2021.8217