Selectively down-regulated PD-L1 by albumin-phenformin nanoparticles mediated mitochondrial dysfunction to stimulate tumor-specific immunological response for enhanced mild-temperature photothermal efficacy

BACKGROUND: Mild-temperature photothermal therapy (mild-PTT) has emerged as a highly promising antitumor strategy by triggering immunogenic cell death (ICD) to elicit both innate and adaptive immune responses for tumor control. However, mild-PTT still leads to the risk of tumor recurrence or metasta...

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Detalles Bibliográficos
Autores principales: Zhou, Zaigang, Jiang, Ning, Chen, Jiashe, Zheng, Chunjuan, Guo, Yuanyuan, Ye, Ruirong, Qi, Ruogu, Shen, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600872/
https://www.ncbi.nlm.nih.gov/pubmed/34794446
http://dx.doi.org/10.1186/s12951-021-01124-8

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