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A novel PDX modeling strategy and its application in metabolomics study for malignant pleural mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare and aggressive carcinoma located in pleural cavity. Due to lack of effective diagnostic biomarkers and therapeutic targets in MPM, the prognosis is extremely poor. Because of difficulties in sample extraction, and the high rate of misdiagnos...

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Detalles Bibliográficos
Autores principales: Chen, Zhongjian, Yang, Chenxi, Guo, Zhenying, Song, Siyu, Gao, Yun, Wang, Ding, Mao, Weimin, Liu, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600931/
https://www.ncbi.nlm.nih.gov/pubmed/34789172
http://dx.doi.org/10.1186/s12885-021-08980-5

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