RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts

RBFOX2, which has a well-established role in alternative splicing, is linked to heart diseases. However, it is unclear whether RBFOX2 has other roles in RNA processing that can influence gene expression in muscle cells, contributing to heart disease. Here, we employ both 3′-end and nanopore cDNA seq...

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Detalles Bibliográficos
Autores principales: Cao, Jun, Verma, Sunil K., Jaworski, Elizabeth, Mohan, Stephanie, Nagasawa, Chloe K., Rayavara, Kempaiah, Sooter, Amanda, Miller, Sierra N., Holcomb, Richard J., Powell, Mason J., Ji, Ping, Elrod, Nathan D., Yildirim, Eda, Wagner, Eric J., Popov, Vsevolod, Garg, Nisha J., Routh, Andrew L., Kuyumcu-Martinez, Muge N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600936/
https://www.ncbi.nlm.nih.gov/pubmed/34731606
http://dx.doi.org/10.1016/j.celrep.2021.109910

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