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A data-driven approach for the detection of internal standard outliers in targeted LC-MS/MS assays
Heavy-labelled internal standard (IS) compounds are commonly used in liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays to control for stochastic and systematic variation. Identifying samples that suffer from unwanted variation is critically important in order to avoid factitiously ina...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600994/ https://www.ncbi.nlm.nih.gov/pubmed/34820670 http://dx.doi.org/10.1016/j.jmsacl.2021.06.001 |