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Direct detection of OXA-48-like carbapenemase variants with and without co-expression of an extended-spectrum β-lactamase from bacterial cell lysates using mass spectrometry

INTRODUCTION: Antibiotic-resistant Gram-negative bacteria are of a growing concern globally, especially those producing enzymes conferring resistance. OXA-48-like carbapenemases hydrolyze most β-lactam antibiotics, with typically low-level hydrolysis of carbapenems, but have limited effect on broad-...

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Detalles Bibliográficos
Autores principales:	McGee, William M., Verma, Arvind, Viirtola, Marjaana, Kronewitter, Scott R., Neil, Jason R., Stephenson, James L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601005/ https://www.ncbi.nlm.nih.gov/pubmed/34820668 http://dx.doi.org/10.1016/j.jmsacl.2021.05.001

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