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β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME

Myeloid-derived suppressor cells (MDSCs) impede antitumor immunity; however, the precise mechanisms that regulate their suppressive function remain unresolved. Identifying these mechanisms could lead to therapeutic interventions to boost cancer immunotherapy efficacy. Here, we reveal that β2 adrener...

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Detalles Bibliográficos
Autores principales:	Mohammadpour, Hemn, MacDonald, Cameron R., McCarthy, Philip L., Abrams, Scott I., Repasky, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601406/ https://www.ncbi.nlm.nih.gov/pubmed/34706232 http://dx.doi.org/10.1016/j.celrep.2021.109883

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