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EHMT2 suppresses the variation of transcriptional switches in the mouse embryo

EHMT2 is the main euchromatic H3K9 methyltransferase. Embryos with zygotic, or maternal mutation in the Ehmt2 gene exhibit variable developmental delay. To understand how EHMT2 prevents variable developmental delay we performed RNA sequencing of mutant and somite stage-matched normal embryos at 8.5–...

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Detalles Bibliográficos
Autores principales:	Zeng, Tie-Bo, Pierce, Nicholas, Liao, Ji, Singh, Purnima, Lau, Kin, Zhou, Wanding, Szabó, Piroska E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601470/ https://www.ncbi.nlm.nih.gov/pubmed/34793451 http://dx.doi.org/10.1371/journal.pgen.1009908

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