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Osteoblast-specific inactivation of p53 results in locally increased bone formation

Inactivation of the tumor suppressor p53 (encoded by the Trp53 gene) is relevant for development and growth of different cancers, including osteosarcoma, a primary bone tumor mostly affecting children and young adolescents. We have previously shown that deficiency of the ribosomal S6 kinase 2 (Rsk2)...

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Detalles Bibliográficos
Autores principales:	Liao, Nannan, Koehne, Till, Tuckermann, Jan, Triviai, Ioanna, Amling, Michael, David, Jean-Pierre, Schinke, Thorsten, Luther, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601510/ https://www.ncbi.nlm.nih.gov/pubmed/34793446 http://dx.doi.org/10.1371/journal.pone.0249894

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