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Boosting BCG with recombinant influenza A virus tuberculosis vaccines increases pulmonary T cell responses but not protection against Mycobacterium tuberculosis infection

The current Mycobacterium bovis BCG vaccine provides inconsistent protection against pulmonary infection with Mycobacterium tuberculosis. Immunity induced by subcutaneous immunization with BCG wanes and does not promote early recruitment of T cell to the lungs after M. tuberculosis infection. Delive...

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Detalles Bibliográficos
Autores principales:	Muflihah, Heni, Flórido, Manuela, Lin, Leon C. W., Xia, Yingju, Triccas, James A., Stambas, John, Britton, Warwick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601556/ https://www.ncbi.nlm.nih.gov/pubmed/34793507 http://dx.doi.org/10.1371/journal.pone.0259829

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