Antibody in Lymphocyte Supernatant (ALS) responses after oral vaccination with live Shigella sonnei vaccine candidates WRSs2 and WRSs3 and correlation with serum antibodies, ASCs, fecal IgA and shedding

The levels of antigen-specific Antibodies in Lymphocyte Supernatant (ALS) using an ELISA are being used to evaluate mucosal immune responses as an alternate to measuring the number of Antibody Secreting Cells (ASCs) using an ELISpot assay. A recently completed trial of two novel S. sonnei live oral...

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Detalles Bibliográficos
Autores principales: Venkatesan, Malabi M., Ballou, Cassandra, Barnoy, Shoshana, McNeal, Monica, El-Khorazaty, Jill, Frenck, Robert, Baqar, Shahida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601580/
https://www.ncbi.nlm.nih.gov/pubmed/34793505
http://dx.doi.org/10.1371/journal.pone.0259361

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