Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity

Pancreatic β-cell failure is a critical event in the onset of both main types of diabetes mellitus but underlying mechanisms are not fully understood. β-cells have low anti-oxidant capacity, making them more susceptible to oxidative stress. In type 1 diabetes (T1D), reactive oxygen species (ROS) are...

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Detalles Bibliográficos
Autores principales: Leenders, Floris, Groen, Nathalie, de Graaf, Natascha, Engelse, Marten A., Rabelink, Ton J., de Koning, Eelco J. P., Carlotti, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601632/
https://www.ncbi.nlm.nih.gov/pubmed/34804002
http://dx.doi.org/10.3389/fimmu.2021.690379

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