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Expression of spindle assembly checkpoint proteins BubR1 and Mad2 expression as potential biomarkers of malignant transformation of oral leukoplakia: an observational cohort study

BACKGROUND: The Spindle Assembly Checkpoint (SAC) is a surveillance mechanism essential to ensure the accuracy of chromosome segregation during mitosis. Our aim was to evaluate the expression of SAC proteins in oral carcinogenesis, and to assess their potential in predicting malignant transformation...

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Detalles Bibliográficos
Autores principales: Monteiro, Luís, Silva, Patrícia, Delgado, Leonor, Amaral, Barbas, Garcês, Fernanda, Salazar, Filomena, Pacheco, José Júlio, Lopes, Carlos, Bousbaa, Hassan, Warnakulasuriya, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601638/
https://www.ncbi.nlm.nih.gov/pubmed/34704983
http://dx.doi.org/10.4317/medoral.24511