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Expression of spindle assembly checkpoint proteins BubR1 and Mad2 expression as potential biomarkers of malignant transformation of oral leukoplakia: an observational cohort study
BACKGROUND: The Spindle Assembly Checkpoint (SAC) is a surveillance mechanism essential to ensure the accuracy of chromosome segregation during mitosis. Our aim was to evaluate the expression of SAC proteins in oral carcinogenesis, and to assess their potential in predicting malignant transformation...
Autores principales: | Monteiro, Luís, Silva, Patrícia, Delgado, Leonor, Amaral, Barbas, Garcês, Fernanda, Salazar, Filomena, Pacheco, José Júlio, Lopes, Carlos, Bousbaa, Hassan, Warnakulasuriya, Saman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601638/ https://www.ncbi.nlm.nih.gov/pubmed/34704983 http://dx.doi.org/10.4317/medoral.24511 |
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