Cargando…

Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways

Hemorrhagic cystitis is an important complication of cyclophosphamide chemotherapy, and current therapies for the disease are limited. The natural flavonoid luteolin (LUT) has significant anti-inflammatory and antioxidant properties, but its protective effect on cyclophosphamide (CYP)-induced bladde...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hengshuai, Zhao, Jiang, Lu, Qudong, Sun, Bishao, Liu, Xin, Yang, Chengfei, Li, Shuai, Li, Longkun, Yi, Shanhong, Yang, Zhenxing, Xu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601811/ https://www.ncbi.nlm.nih.gov/pubmed/34804174 http://dx.doi.org/10.1155/2021/1718709

Ejemplares similares

Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1
por: Lu, Qudong, et al.
Publicado: (2021)

Inhibition of CXCR4 in Spinal Cord and DRG with AMD3100 Attenuates Colon-Bladder Cross-Organ Sensitization
por: Zhang, Hengshuai, et al.
Publicado: (2022)

Increased Piezo1 channel activity in interstitial Cajal-like cells induces bladder hyperactivity by functionally interacting with NCX1 in rats with cyclophosphamide-induced cystitis
por: Liu, Qian, et al.
Publicado: (2018)

Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro
por: Sun, Bishao, et al.
Publicado: (2019)

Corrigendum to “Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro”
por: Sun, Bishao, et al.
Publicado: (2021)

TrkA inhibition alleviates bladder overactivity in cyclophosphamide-induced cystitis by targeting hyperpolarization-activated cyclic nucleotide-gated channels
por: Liu, Qian, et al.
Publicado: (2023)

Cyclophosphamide-induced HCN1 channel upregulation in interstitial Cajal-like cells leads to bladder hyperactivity in mice
por: Liu, Qian, et al.
Publicado: (2017)

The NLRP3 Inflammasome Inhibitor Dapansutrile Attenuates Cyclophosphamide-Induced Interstitial Cystitis
por: Kiran, Sonia, et al.
Publicado: (2022)

Detrusor Myocyte Autophagy Protects the Bladder Function via Inhibiting the Inflammation in Cyclophosphamide-Induced Cystitis in Rats
por: Zhao, Jiang, et al.
Publicado: (2015)

Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
por: Muri, Jonathan, et al.
Publicado: (2020)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction
por: Yang, Chun, et al.
Publicado: (2019)

Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway
por: Liu, Qi, et al.
Publicado: (2020)

The protective effect of luteolin on the depression-related dry eye disorder through Sirt1/NF-κB/NLRP3 pathway
por: Xie, Mingxia, et al.
Publicado: (2023)

Diallyl Disulfide Prevents Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats through the Inhibition of Oxidative Damage, MAPKs, and NF-κB Pathways
por: Kim, Sung Hwan, et al.
Publicado: (2015)

TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)

Morusin exerts anti-cancer activity in renal cell carcinoma by disturbing MAPK signaling pathways
por: Yang, Chengfei, et al.
Publicado: (2020)

Linarin prevents LPS-induced acute lung injury by suppressing oxidative stress and inflammation via inhibition of TXNIP/NLRP3 and NF-κB pathways
por: Han, Xiang, et al.
Publicado: (2018)

Emphysematous Cystitis in a Patient Receiving Cyclophosphamide
por: Al Zein, Said
Publicado: (2021)

Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation
por: Jiang, Jianjun, et al.
Publicado: (2021)

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
por: Liu, Fangfang, et al.
Publicado: (2022)

Interleukin‐6/signal transducer and activator of transcription 3 promotes prostate cancer resistance to androgen deprivation therapy via regulating pituitary tumor transforming gene 1 expression
por: Huang, Shengquan, et al.
Publicado: (2018)

PDE1A polymorphism contributes to the susceptibility of nephrolithiasis
por: Yang, Zhenxing, et al.
Publicado: (2017)

MIF mediates bladder pain, not inflammation, in cyclophosphamide cystitis
por: Ma, Fei, et al.
Publicado: (2019)

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
por: An, Xin, et al.
Publicado: (2020)

New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats
por: Ding, Chunchun, et al.
Publicado: (2016)

High-definition ultrasound characterization of acute cyclophosphamide-induced cystitis in the mouse
por: Lee, Toy G., et al.
Publicado: (2020)

Normalization of magnesium deficiency attenuated mechanical allodynia, depressive-like behaviors, and memory deficits associated with cyclophosphamide-induced cystitis by inhibiting TNF-α/NF-κB signaling in female rats
por: Chen, Jia-Liang, et al.
Publicado: (2020)

Huaiqihuang (HQH) granule alleviates cyclophosphamide-induced nephrotoxicity via suppressing the MAPK/NF-κB pathway and NLRP3 inflammasome activation
por: Zhang, Yueming, et al.
Publicado: (2021)

Expressions of Uroplakins in the Mouse Urinary Bladder with Cyclophosphamide-Induced Cystitis
por: Choi, Seong Hoo, et al.
Publicado: (2009)

Rho kinase inhibition ameliorates cyclophosphamide-induced cystitis in rats
por: Wróbel, Andrzej, et al.
Publicado: (2017)

The Isopropyl Gallate Counteracts Cyclophosphamide-Induced Hemorrhagic Cystitis in Mice
por: Almeida de Oliveira, Lucas Solyano, et al.
Publicado: (2022)

Different Intensity Exercise Preconditions Affect Cardiac Function of Exhausted Rats through Regulating TXNIP/TRX/NF-ĸB(p65)/NLRP3 Inflammatory Pathways
por: Li, Yuemin, et al.
Publicado: (2020)

Loss of NLRP3 increases bacterial cystitis via IRAKM
por: Sun, Jie, et al.
Publicado: (2022)

Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases
por: Liang, Liuqin, et al.
Publicado: (2017)

Effects of Hypoxic Environment on Periodontal Tissue through the ROS/TXNIP/NLRP3 Inflammasome Pathway
por: Zhu, Rui, et al.
Publicado: (2022)

Correction to: Normalization of magnesium deficiency attenuated mechanical allodynia, depressive-like behaviors, and memory deficits associated with cyclophosphamide-induced cystitis by inhibiting TNF-α/NF-κB signaling in female rats
por: Chen, Jia-Liang, et al.
Publicado: (2021)

4-PBA inhibits endoplasmic reticulum stress to improve autophagic flux in the treatment of protamine/lipopolysaccharide-induced interstitial cystitis in rats
por: Jia, Li, et al.
Publicado: (2023)

Luteolin reduces inflammation in Staphylococcus aureus-induced mastitis by inhibiting NF-κB activation and MMPs expression
por: Guo, Ying-fang, et al.
Publicado: (2017)

TXNIP Participated in NLRP3-Mediated Inflammation in a Rat Model of Cervical Spondylotic Myelopathy
por: Liu, Peisheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u26bq9k89kue39k7lsqe7l7p4r