Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the latency-associated peptide (LAP) of TGF-β on their surface and LAP(Hi) MCs that stimulate Foxp3(+) Tregs while inhibiting effector T cell proli...

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Detalles Bibliográficos
Autores principales: Gabriely, Galina, Ma, Duanduan, Siddiqui, Shafiuddin, Sun, Linqing, Skillin, Nathaniel P., Abou-El-Hassan, Hadi, Moreira, Thais G., Donnelly, Dustin, da Cunha, Andre P., Fujiwara, Mai, Walton, Lena R., Patel, Amee, Krishnan, Rajesh, Levine, Stuart S., Healy, Brian C., Rezende, Rafael M., Murugaiyan, Gopal, Weiner, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602030/
https://www.ncbi.nlm.nih.gov/pubmed/34820606
http://dx.doi.org/10.1016/j.isci.2021.103347

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