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Lorcaserin Inhibit Glucose-Stimulated Insulin Secretion and Calcium Influx in Murine Pancreatic Islets

Lorcaserin is a serotonergic agonist specific to the 5-hydroxytryptamine 2c receptor (5-HT(2C)R) that is FDA approved for the long-term management of obesity with or without at least one weight-related comorbidity. Lorcaserin can restrain patients’ appetite and improve insulin sensitivity and hyperi...

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Detalles Bibliográficos
Autores principales: Jing, Muhan, Wang, Shanshan, Li, Ding, Wang, Zeyu, Li, Ziwen, Lu, Yichen, Sun, Tong, Qiu, Chen, Chen, Fang, Yu, Haijuan, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602196/
https://www.ncbi.nlm.nih.gov/pubmed/34803706
http://dx.doi.org/10.3389/fphar.2021.761966