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Social stress drives the multi-wave dynamics of COVID-19 outbreaks

The dynamics of epidemics depend on how people's behavior changes during an outbreak. At the beginning of the epidemic, people do not know about the virus, then, after the outbreak of epidemics and alarm, they begin to comply with the restrictions and the spreading of epidemics may decline. Ove...

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Autores principales: Kastalskiy, Innokentiy A., Pankratova, Evgeniya V., Mirkes, Evgeny M., Kazantsev, Victor B., Gorban, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602246/
https://www.ncbi.nlm.nih.gov/pubmed/34795311
http://dx.doi.org/10.1038/s41598-021-01317-z
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author Kastalskiy, Innokentiy A.
Pankratova, Evgeniya V.
Mirkes, Evgeny M.
Kazantsev, Victor B.
Gorban, Alexander N.
author_facet Kastalskiy, Innokentiy A.
Pankratova, Evgeniya V.
Mirkes, Evgeny M.
Kazantsev, Victor B.
Gorban, Alexander N.
author_sort Kastalskiy, Innokentiy A.
collection PubMed
description The dynamics of epidemics depend on how people's behavior changes during an outbreak. At the beginning of the epidemic, people do not know about the virus, then, after the outbreak of epidemics and alarm, they begin to comply with the restrictions and the spreading of epidemics may decline. Over time, some people get tired/frustrated by the restrictions and stop following them (exhaustion), especially if the number of new cases drops down. After resting for a while, they can follow the restrictions again. But during this pause the second wave can come and become even stronger then the first one. Studies based on SIR models do not predict the observed quick exit from the first wave of epidemics. Social dynamics should be considered. The appearance of the second wave also depends on social factors. Many generalizations of the SIR model have been developed that take into account the weakening of immunity over time, the evolution of the virus, vaccination and other medical and biological details. However, these more sophisticated models do not explain the apparent differences in outbreak profiles between countries with different intrinsic socio-cultural features. In our work, a system of models of the COVID-19 pandemic is proposed, combining the dynamics of social stress with classical epidemic models. Social stress is described by the tools of sociophysics. The combination of a dynamic SIR-type model with the classical triad of stages of the general adaptation syndrome, alarm-resistance-exhaustion, makes it possible to describe with high accuracy the available statistical data for 13 countries. The sets of kinetic constants corresponding to optimal fit of model to data were found. These constants characterize the ability of society to mobilize efforts against epidemics and maintain this concentration over time and can further help in the development of management strategies specific to a particular society.
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spelling pubmed-86022462021-11-19 Social stress drives the multi-wave dynamics of COVID-19 outbreaks Kastalskiy, Innokentiy A. Pankratova, Evgeniya V. Mirkes, Evgeny M. Kazantsev, Victor B. Gorban, Alexander N. Sci Rep Article The dynamics of epidemics depend on how people's behavior changes during an outbreak. At the beginning of the epidemic, people do not know about the virus, then, after the outbreak of epidemics and alarm, they begin to comply with the restrictions and the spreading of epidemics may decline. Over time, some people get tired/frustrated by the restrictions and stop following them (exhaustion), especially if the number of new cases drops down. After resting for a while, they can follow the restrictions again. But during this pause the second wave can come and become even stronger then the first one. Studies based on SIR models do not predict the observed quick exit from the first wave of epidemics. Social dynamics should be considered. The appearance of the second wave also depends on social factors. Many generalizations of the SIR model have been developed that take into account the weakening of immunity over time, the evolution of the virus, vaccination and other medical and biological details. However, these more sophisticated models do not explain the apparent differences in outbreak profiles between countries with different intrinsic socio-cultural features. In our work, a system of models of the COVID-19 pandemic is proposed, combining the dynamics of social stress with classical epidemic models. Social stress is described by the tools of sociophysics. The combination of a dynamic SIR-type model with the classical triad of stages of the general adaptation syndrome, alarm-resistance-exhaustion, makes it possible to describe with high accuracy the available statistical data for 13 countries. The sets of kinetic constants corresponding to optimal fit of model to data were found. These constants characterize the ability of society to mobilize efforts against epidemics and maintain this concentration over time and can further help in the development of management strategies specific to a particular society. Nature Publishing Group UK 2021-11-18 /pmc/articles/PMC8602246/ /pubmed/34795311 http://dx.doi.org/10.1038/s41598-021-01317-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kastalskiy, Innokentiy A.
Pankratova, Evgeniya V.
Mirkes, Evgeny M.
Kazantsev, Victor B.
Gorban, Alexander N.
Social stress drives the multi-wave dynamics of COVID-19 outbreaks
title Social stress drives the multi-wave dynamics of COVID-19 outbreaks
title_full Social stress drives the multi-wave dynamics of COVID-19 outbreaks
title_fullStr Social stress drives the multi-wave dynamics of COVID-19 outbreaks
title_full_unstemmed Social stress drives the multi-wave dynamics of COVID-19 outbreaks
title_short Social stress drives the multi-wave dynamics of COVID-19 outbreaks
title_sort social stress drives the multi-wave dynamics of covid-19 outbreaks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602246/
https://www.ncbi.nlm.nih.gov/pubmed/34795311
http://dx.doi.org/10.1038/s41598-021-01317-z
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