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Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway

Renal fibrosis is the most common pathological manifestation of a wide variety of chronic kidney disease. Increased extracellular matrix (ECM) secretion and enhanced microenvironment stiffening aggravate the progression of renal fibrosis. However, the related mechanisms remain unclear. Here, we eval...

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Detalles Bibliográficos
Autores principales: Fu, Yuanyuan, Wan, Pengzhi, Zhang, Jie, Li, Xue, Xing, Jia, Zou, Yu, Wang, Kaiyue, Peng, Hui, Zhu, Qizhuo, Cao, Liu, Zhai, Xiaoyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602364/
https://www.ncbi.nlm.nih.gov/pubmed/34805150
http://dx.doi.org/10.3389/fcell.2021.741060