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Elevated Neddylation Pathway Promotes Th2 Cells Infiltration by Transactivating STAT5A in Hepatocellular Carcinoma
Neddylation is a process in which a ubiquitin-like molecule NEDD8 is conjugated to a lysine residue of the substrate protein via successive enzymatic cascade reactions. Inactivation of neddylation pathway triggers tumor cell apoptosis or senescence to suppress the tumor growth. So far, there has bee...
Autores principales: | Zhou, Lisha, Zhang, Luyi, Chen, Siyuan, Sun, Dongsheng, Qu, Jianhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602568/ https://www.ncbi.nlm.nih.gov/pubmed/34804916 http://dx.doi.org/10.3389/fonc.2021.709170 |
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