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Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver

Recent studies demonstrated reduced blood lysosomal acid lipase (LAL) activity in patients with nonalcoholic fatty liver disease (NAFLD). We aimed to verify hepatic LAL protein content and activity in in vitro and in vivo models of fat overload and in NAFLD patients. LAL protein content and activity...

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Detalles Bibliográficos
Autores principales:	Carotti, Simone, Lettieri-Barbato, Daniele, Piemonte, Fiorella, Ruggiero, Sergio, Rosina, Marco, Zalfa, Francesca, Zingariello, Maria, Arciprete, Francesca, Valentini, Francesco, Francesconi, Maria, D’Amico, Jessica, De Vincentis, Antonio, Baiocchini, Andrea, Perrone, Giuseppe, Antonelli-Incalzi, Raffaele, Morini, Sergio, Picardi, Antonio, Aquilano, Katia, Vespasiani-Gentilucci, Umberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602623/ https://www.ncbi.nlm.nih.gov/pubmed/34795230 http://dx.doi.org/10.1038/s41419-021-04382-4

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