Cargando…

Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts

Crohn’s disease is an inflammatory disease of the gastrointestinal tract characterized by an aberrant response to microbial and environmental triggers. This includes an altered microbiome dominated by Enterobacteriaceae and in particular adherent-invasive E. coli (AIEC). Clinical evidence implicates...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shaler, Christopher R., Parco, Alexandra A., Elhenawy, Wael, Dourka, Jasmeen, Jury, Jennifer, Verdu, Elena F., Coombes, Brian K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602651/ https://www.ncbi.nlm.nih.gov/pubmed/34795263 http://dx.doi.org/10.1038/s41467-021-26992-4

Ejemplares similares

Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts
por: Sassone-Corsi, Martina, et al.
Publicado: (2022)

Shifting microbiomes: pathobionts hiding in our guts
por: Cordell, Barbara J.
Publicado: (2023)

Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver
por: Tsugawa, Hitoshi, et al.
Publicado: (2023)

Adaptation of the gut pathobiont Enterococcus faecalis to deoxycholate and taurocholate bile acids
por: Repoila, F., et al.
Publicado: (2022)

Isethionate is an intermediate in the degradation of sulfoacetate by the human gut pathobiont Bilophila wadsworthia
por: Liu, Xumei, et al.
Publicado: (2023)

Editorial: Pathogens, Pathobionts, and Autoimmunity
por: Spatz, Linda A., et al.
Publicado: (2021)

CRISPR-Cas Systems in Bacteroides fragilis, an Important Pathobiont in the Human Gut Microbiome
por: Tajkarimi, Mehrdad, et al.
Publicado: (2017)

IL-10 and IL-22 in Mucosal Immunity: Driving Protection and Pathology
por: Wei, Hua-Xing, et al.
Publicado: (2020)

Gut Anaerobes Capable of Chicken Caecum Colonisation
por: Kubasova, Tereza, et al.
Publicado: (2019)

Strong pathogen competition in neonatal gut colonisation
por: Mäklin, Tommi, et al.
Publicado: (2022)

Draft Genome Sequence of Lactobacillus brevis Strain EW, a Drosophila Gut Pathobiont
por: Kim, Eun-Kyoung, et al.
Publicado: (2013)

Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota
por: Arimatsu, Kei, et al.
Publicado: (2014)

Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis
por: Lee, June-Chul, et al.
Publicado: (2017)

c-Maf-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont
por: Xu, Mo, et al.
Publicado: (2018)

Pathobionts from chemically disrupted gut microbiota induce insulin-dependent diabetes in mice
por: Yang, Xin, et al.
Publicado: (2023)

Dietary fat-induced taurocholic acid production promotes pathobiont and colitis in IL-10(−/−) mice
por: Devkota, Suzanne, et al.
Publicado: (2012)

Colonizing Microbes, IL-10 and IL-22: Keeping the Peace at the Mucosal Surface
por: Kidess, Evelien, et al.
Publicado: (2021)

The Role of IL-33 in Gut Mucosal Inflammation
por: Pastorelli, Luca, et al.
Publicado: (2013)

A polymicrobial view of disease potential in Crohn's-associated adherent-invasive E. coli
por: Elhenawy, Wael, et al.
Publicado: (2017)

Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection
por: Klatt, Nichole R., et al.
Publicado: (2012)

Klebsiella oxytoca expands in cancer cachexia and acts as a gut pathobiont contributing to intestinal dysfunction
por: Pötgens, Sarah A., et al.
Publicado: (2018)

A15 GENETIC OR DIET-ASSOCIATED DEFECTS IN MUCUS FACILITATE ULCERATIVE COLITIS PATHOBIONT-DRIVEN COLITIS
por: Yang, H, et al.
Publicado: (2023)

Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis
por: Imai, Jin, et al.
Publicado: (2019)

Dysbiosis by neutralizing commensal mediated inhibition of pathobionts
por: Herrero, Esteban Rodriguez, et al.
Publicado: (2016)

Gastrointestinal Pathobionts in Pediatric Crohn's Disease Patients
por: Purcell, Rachel V., et al.
Publicado: (2018)

The Role of Butyrate in Attenuating Pathobiont-Induced Hyperinflammation
por: Chen, Jiezhong, et al.
Publicado: (2020)

When Pathobiont-Carbohydrate Interaction Turns Bittersweet!
por: Barnich, Nicolas, et al.
Publicado: (2021)

Gut mucosal colonisation with extended-spectrum beta-lactamase producing Enterobacteriaceae in sub-Saharan Africa: a systematic review and meta-analysis
por: Lewis, Joseph M., et al.
Publicado: (2020)

Acute Infectious Gastroenteritis Potentiates a Crohn's Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period
por: Small, Cherrie L., et al.
Publicado: (2016)

Pathobiont release from dysbiotic gut microbiota biofilms in intestinal inflammatory diseases: a role for iron?
por: Buret, Andre Gerald, et al.
Publicado: (2019)

Oral Pathobiont-Induced Changes in Gut Microbiota Aggravate the Pathology of Nonalcoholic Fatty Liver Disease in Mice
por: Yamazaki, Kyoko, et al.
Publicado: (2021)

Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus
por: Pasquereau-Kotula, Ewa, et al.
Publicado: (2023)

Vascularisation is not necessary for gut colonisation by enteric neural crest cells()
por: Delalande, Jean-Marie, et al.
Publicado: (2014)

Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation
por: Ji, Yong Woo, et al.
Publicado: (2017)

Correction: Acute Infectious Gastroenteritis Potentiates a Crohn's Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period
por: Small, Cherrie L., et al.
Publicado: (2018)

The Complete Genome Sequence of the Murine Pathobiont Helicobacter typhlonius
por: Frank, Jeroen, et al.
Publicado: (2016)

Putative Pathobionts in HLA-B27-Associated Spondyloarthropathy
por: Gill, Tejpal, et al.
Publicado: (2021)

Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation
por: Kelly, Alanna M., et al.
Publicado: (2022)

A gut pathobiont synergizes with the microbiota to instigate inflammatory disease marked by immunoreactivity against other symbionts but not itself
por: Gomes-Neto, João Carlos, et al.
Publicado: (2017)

Crohn’s Disease Pathobiont Adherent-Invasive E coli Disrupts Epithelial Mitochondrial Networks With Implications for Gut Permeability
por: Mancini, Nicole L., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d277g1ghn6fnkupnkg7blv4dhp