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MFAP4 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Through Regulation of Macrophage Infiltration and Activity
Objective: Abdominal aortic aneurysm (AAA) is a common age-related vascular disease characterized by progressive weakening and dilatation of the aortic wall. Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix (ECM) protein involved in the induction of vascular remodeling. This st...
Autores principales: | Pilecki, Bartosz, de Carvalho, Paulo V. S. D., Kirketerp-Møller, Katrine L., Schlosser, Anders, Kejling, Karin, Dubik, Magdalena, Madsen, Nicklas P., Stubbe, Jane, Hansen, Pernille B. L., Andersen, Thomas L., Moeller, Jesper B., Marcussen, Niels, Azevedo, Vasco, Hvidsten, Svend, Baun, Christina, Shi, Guo-Ping, Lindholt, Jes S., Sorensen, Grith L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602692/ https://www.ncbi.nlm.nih.gov/pubmed/34805319 http://dx.doi.org/10.3389/fcvm.2021.764337 |
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