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Splenic Transcriptional Responses in Severe Visceral Leishmaniasis: Impaired Leukocyte Chemotaxis and Cell Cycle Arrest
Structural changes in the spleen have been reported in several infectious diseases. In visceral leishmaniasis (VL), a severe parasitic disease caused by Leishmania spp., the loss of white pulp accompanies a severe clinical presentation. Hamster model reproduces aspects of human VL progression. In th...
Autores principales: | de Melo, Caroline Vilas Boas, Guimarães Torres, Felipe, Hermida, Micely D’El-Rei, Fontes, Jonathan L. M., Mesquita, Bianca Ramos, Brito, Reginaldo, Ramos, Pablo Ivan P., Fernandes, Gabriel R., Freitas, Luiz Antônio Rodrigues, Khouri, Ricardo, Costa, Carlos Henrique Nery, dos-Santos, Washington L. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602831/ https://www.ncbi.nlm.nih.gov/pubmed/34804009 http://dx.doi.org/10.3389/fimmu.2021.716314 |
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