Cargando…

Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targets

AIM: Insulin-like growth factor-1 receptor (IGF-1R) is one of the main members of the tyrosine protein kinase receptor family. This receptor binds insulin-like growth factor-1 (IGF-1) with a high affinity. IGF-1 is a member of a family of proteins involved in mediating growth and development. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yinqi, Gao, Chengqi, Cao, Fei, Wu, Ying, Chen, Shuanggang, Han, Xue, Mo, Jingqin, Qiu, Zhiyu, Fan, Weijun, Zhou, Penghui, Shen, Lujun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602838/ https://www.ncbi.nlm.nih.gov/pubmed/34804946 http://dx.doi.org/10.3389/fonc.2021.755341

Ejemplares similares

YTHDF1 Is a Potential Pan-Cancer Biomarker for Prognosis and Immunotherapy
por: Hu, Jian, et al.
Publicado: (2021)

Role of PRDM1 in Tumor Immunity and Drug Response: A Pan-Cancer Analysis
por: Shen, Lujun, et al.
Publicado: (2020)

A pan-cancer landscape of IGF2BPs and their association with prognosis, stemness and tumor immune microenvironment
por: Shao, Wei, et al.
Publicado: (2023)

Understanding the Key to Targeting the IGF Axis in Cancer: A Biomarker Assessment
por: Lodhia, Kunal Amratlal, et al.
Publicado: (2015)

Surveillance Strategy for Patients With BCLC Stage B Hepatocellular Carcinoma After Achieving Complete Remission: Data From the Real World
por: Wu, Ying, et al.
Publicado: (2020)

Evaluating the local expression pattern of IGF-1R in tumor tissues and the circulating levels of IGF-1, IGFBP-1, and IGFBP-3 in the blood of patients with different primary bone tumors
por: Vaezi, Mohammad Amin, et al.
Publicado: (2023)

Hepatocellular Carcinoma Within the Milan Criteria: A Novel Inflammation-Based Nomogram System to Assess the Outcomes of Ablation
por: Chen, Shuanggang, et al.
Publicado: (2020)

Recurrence Beyond the Milan Criteria of HBV-Related Single Hepatocellular Carcinoma of 2–3 cm: Comparison of Resection and Ablation
por: Chen, Shuanggang, et al.
Publicado: (2021)

Durable Response of Spinal Chordoma to Combined Inhibition of IGF-1R and EGFR
por: Aleksic, Tamara, et al.
Publicado: (2016)

Efficacy Of Apatinib In Transcatheter Arterial Chemoembolization (TACE) Refractory Intermediate And Advanced-Stage Hepatocellular carcinoma：A Propensity Score Matching Analysis
por: Qiu, Zhiyu, et al.
Publicado: (2019)

Genetic Polymorphisms of IGF1 and IGF1R Genes and Their Effects on Growth Traits in Hulun Buir Sheep
por: Ding, Ning, et al.
Publicado: (2022)

Mutual connected IL-6, EGFR and LIN28/Let7-related mechanisms modulate PD-L1 and IGF upregulation in HNSCC using immunotherapy
por: Li, Junjun, et al.
Publicado: (2023)

IGF-1 Interacted With Obesity in Prognosis Prediction in HER2-Positive Breast Cancer Patients
por: Tong, Yiwei, et al.
Publicado: (2020)

Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls
por: Chang, Hua-Pin, et al.
Publicado: (2018)

IGF-IR: a new prognostic biomarker for human glioblastoma
por: Maris, C, et al.
Publicado: (2015)

Diagnostic Utility of IGF2BP1 and Its Targets as Potential Biomarkers in ETV6-RUNX1 Positive B-Cell Acute Lymphoblastic Leukemia
por: Sharma, Gunjan, et al.
Publicado: (2021)

Cross-Talk between Adiponectin and IGF-IR in Breast Cancer
por: Mauro, Loredana, et al.
Publicado: (2015)

The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy
por: Vigneri, Paolo Giovanni, et al.
Publicado: (2015)

Autocrine IGF-1 Action in Adipocytes Controls Systemic IGF-1 Concentrations and Growth
por: Klöting, Nora, et al.
Publicado: (2008)

The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells
por: Xu, Dan-dan, et al.
Publicado: (2018)

Role of IGF2BPs in head and neck squamous cell carcinoma
por: Wu, Kainan, et al.
Publicado: (2022)

Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer
por: Sipos, Ferenc, et al.
Publicado: (2017)

IGF2 and IGF1R mRNAs Are Detectable in Human Spermatozoa
por: Cannarella, Rossella, et al.
Publicado: (2020)

Identification of IGF2BP3 as an Adverse Prognostic Biomarker of Gliomas
por: Sun, Chao, et al.
Publicado: (2021)

Polyploid Adipose Stem Cells Shift the Balance of IGF1/IGFBP2 to Promote the Growth of Breast Cancer
por: Fajka-Boja, Roberta, et al.
Publicado: (2020)

m(6)A-binding protein IGF2BP1 promotes the malignant phenotypes of lung adenocarcinoma
por: Wu, Hansheng, et al.
Publicado: (2022)

Correlation of serum IGF-1, AGEs and their receptors with the risk of colorectal cancer in patients with type 2 diabetes mellitus
por: Chen, Zeng, et al.
Publicado: (2023)

Does Reduced IGF-1R Signaling in Igf1r (+/−) Mice Alter Aging?
por: Bokov, Alex F., et al.
Publicado: (2011)

The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth
por: Ouni, Meriem, et al.
Publicado: (2015)

Various phenotypes of short stature with heterozygous IGF-1 receptor (IGF1R) mutations
por: Kawashima-Sonoyama, Yuki, et al.
Publicado: (2022)

Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes
por: Vella, A., et al.
Publicado: (2008)

Sequential activation of uterine epithelial IGF1R by stromal IGF1 and embryonic IGF2 directs normal uterine preparation for embryo implantation
por: Zhou, Chan, et al.
Publicado: (2021)

Pan-Cancer Analysis of the Mitophagy-Related Protein PINK1 as a Biomarker for the Immunological and Prognostic Role
por: Zhu, Lizhe, et al.
Publicado: (2020)

Pan-cancer analysis identified OAS1 as a potential prognostic biomarker for multiple tumor types
por: Jiang, Shan, et al.
Publicado: (2023)

IGF/IGF-1R signal pathway in pain: a promising therapeutic target
por: Ma, Lulin, et al.
Publicado: (2023)

Investigation of Igf-1, Igf-Bp3 and Igf-Bp5 levels in umbilical cord blood of infants with developmental dysplasia of the hip
por: DEMİREL, Esra, et al.
Publicado: (2023)

The clinicopathological and prognostic significances of IGF-1R and Livin expression in patients with colorectal cancer
por: Zhang, Zhenling, et al.
Publicado: (2022)

Role of IGF-1/IGF-1R in regulation of invasion in DU145 prostate cancer cells
por: Saikali, Zeina, et al.
Publicado: (2008)

Cyclic glycine-proline regulates IGF-1 homeostasis by altering the binding of IGFBP-3 to IGF-1
por: Guan, Jian, et al.
Publicado: (2014)

Hypoxia‐induced ELF3 promotes tumor angiogenesis through IGF1/IGF1R
por: Seo, Seung Hee, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_32qknpelbdvg093ldidqn7i7v4