Monitoring Tacrolimus Concentrations in Whole Blood and Peripheral Blood Mononuclear Cells: Inter- and Intra-Patient Variability in a Cohort of Pediatric Patients

Tacrolimus (TAC) is a first-choice immunosuppressant for solid organ transplantation, characterized by high potential for drug-drug interactions, significant inter- and intra-patient variability, and narrow therapeutic index. Therapeutic drug monitoring (TDM) of TAC concentrations in whole blood (WB...

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Detalles Bibliográficos
Autores principales: De Nicolò, Amedeo, Pinon, Michele, Palermiti, Alice, Nonnato, Antonello, Manca, Alessandra, Mula, Jacopo, Catalano, Silvia, Tandoi, Francesco, Romagnoli, Renato, D’Avolio, Antonio, Calvo, Pier Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602893/
https://www.ncbi.nlm.nih.gov/pubmed/34803692
http://dx.doi.org/10.3389/fphar.2021.750433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602893/
https://www.ncbi.nlm.nih.gov/pubmed/34803692
http://dx.doi.org/10.3389/fphar.2021.750433

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