Monocyte dysfunction in decompensated cirrhosis is mediated by the prostaglandin E2-EP4 pathway

BACKGROUND & AIMS: Infection is a major problem in advanced liver disease secondary to monocyte dysfunction. Elevated prostaglandin (PG)E(2) is a mediator of monocyte dysfunction in cirrhosis; thus, we examined PGE(2) signalling in outpatients with ascites and in patients hospitalised with acute...

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Detalles Bibliográficos
Autores principales: Maini, Alexander A., Becares, Natalia, China, Louise, Tittanegro, Thais H., Patel, Amit, De Maeyer, Roel P.H., Zakeri, Nekisa, Long, Tu Vinh, Ly, Lucy, Gilroy, Derek W., O’Brien, Alastair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603213/
https://www.ncbi.nlm.nih.gov/pubmed/34825153
http://dx.doi.org/10.1016/j.jhepr.2021.100332

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