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Bicuspid aortic valve repair: outcomes after 17 years of experience

 : OBJECTIVES: This study presents the results of 17 years of experience with bicuspid aortic valve (BAV) repair and the analysis of factors associated with repair failure and early echocardiographic outcome. METHODS: Between 2003 and 2020, a total of 206 patients [mean age: 44.5 ± 15.2 years; 152 m...

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Autores principales: Jasinski, Marek J, Kosiorowska, Kinga, Gocol, Radoslaw, Jasinski, Jakub, Nowicki, Rafal, Bielicki, Grzegorz, Berezowski, Mikolaj, Przybylski, Roman, Obremska, Marta, Lukaszewski, Marceli, Larysz, Anna, Kansy, Andrzej, Deja, Marek A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603241/
https://www.ncbi.nlm.nih.gov/pubmed/33889957
http://dx.doi.org/10.1093/ejcts/ezab176
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author Jasinski, Marek J
Kosiorowska, Kinga
Gocol, Radoslaw
Jasinski, Jakub
Nowicki, Rafal
Bielicki, Grzegorz
Berezowski, Mikolaj
Przybylski, Roman
Obremska, Marta
Lukaszewski, Marceli
Larysz, Anna
Kansy, Andrzej
Deja, Marek A
author_facet Jasinski, Marek J
Kosiorowska, Kinga
Gocol, Radoslaw
Jasinski, Jakub
Nowicki, Rafal
Bielicki, Grzegorz
Berezowski, Mikolaj
Przybylski, Roman
Obremska, Marta
Lukaszewski, Marceli
Larysz, Anna
Kansy, Andrzej
Deja, Marek A
author_sort Jasinski, Marek J
collection PubMed
description  : OBJECTIVES: This study presents the results of 17 years of experience with bicuspid aortic valve (BAV) repair and the analysis of factors associated with repair failure and early echocardiographic outcome. METHODS: Between 2003 and 2020, a total of 206 patients [mean age: 44.5 ± 15.2 years; 152 males (74%)] with BAV insufficiency with or without aortic dilatation underwent elective aortic valve repair performed by a single surgeon with a mean follow-up of 5 ± 3.5 years. The transthoracic echocardiography examinations were reported. RESULTS: There were no deaths during the hospital stay, and all but 1 patient survived the follow-up period (99.5%). Overall, 10 patients (5%) developed severe insufficiency and 2 (1%) developed aortic dilatation requiring reoperation. Freedom from reoperation at 7 years reached 91.8%. Type 2 BAV configuration [hazard ratio (HR) 3.9; 95% confidence interval (CI): 1.01–60; P = 0.049], no sinotubular junction remodelling (HR 7; 95% CI: 1.7–23; P = 0.005), no circumferential annuloplasty (HR 3.9; 95% CI: 1.01–64; P = 0.047) and leaflet resection (HR 5.7; 95% CI 1.2–13. P = 0.017) have been identified as a risk factor of redo operation. Parameters of the postoperative left ventricle reverse remodelling improved significantly early after the operation and later at 2 years evaluation. CONCLUSIONS: The repair of BAV offers good short- and mid-term results providing a significant reverse left ventricular remodelling. Type 0 BAV preoperative configuration, circumferential annuloplasty and sinotubular junction remodelling are associated with better repair durability.
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spelling pubmed-86032412021-11-22 Bicuspid aortic valve repair: outcomes after 17 years of experience Jasinski, Marek J Kosiorowska, Kinga Gocol, Radoslaw Jasinski, Jakub Nowicki, Rafal Bielicki, Grzegorz Berezowski, Mikolaj Przybylski, Roman Obremska, Marta Lukaszewski, Marceli Larysz, Anna Kansy, Andrzej Deja, Marek A Eur J Cardiothorac Surg Conventional Aortic Surgery  : OBJECTIVES: This study presents the results of 17 years of experience with bicuspid aortic valve (BAV) repair and the analysis of factors associated with repair failure and early echocardiographic outcome. METHODS: Between 2003 and 2020, a total of 206 patients [mean age: 44.5 ± 15.2 years; 152 males (74%)] with BAV insufficiency with or without aortic dilatation underwent elective aortic valve repair performed by a single surgeon with a mean follow-up of 5 ± 3.5 years. The transthoracic echocardiography examinations were reported. RESULTS: There were no deaths during the hospital stay, and all but 1 patient survived the follow-up period (99.5%). Overall, 10 patients (5%) developed severe insufficiency and 2 (1%) developed aortic dilatation requiring reoperation. Freedom from reoperation at 7 years reached 91.8%. Type 2 BAV configuration [hazard ratio (HR) 3.9; 95% confidence interval (CI): 1.01–60; P = 0.049], no sinotubular junction remodelling (HR 7; 95% CI: 1.7–23; P = 0.005), no circumferential annuloplasty (HR 3.9; 95% CI: 1.01–64; P = 0.047) and leaflet resection (HR 5.7; 95% CI 1.2–13. P = 0.017) have been identified as a risk factor of redo operation. Parameters of the postoperative left ventricle reverse remodelling improved significantly early after the operation and later at 2 years evaluation. CONCLUSIONS: The repair of BAV offers good short- and mid-term results providing a significant reverse left ventricular remodelling. Type 0 BAV preoperative configuration, circumferential annuloplasty and sinotubular junction remodelling are associated with better repair durability. Oxford University Press 2021-04-23 /pmc/articles/PMC8603241/ /pubmed/33889957 http://dx.doi.org/10.1093/ejcts/ezab176 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Conventional Aortic Surgery
Jasinski, Marek J
Kosiorowska, Kinga
Gocol, Radoslaw
Jasinski, Jakub
Nowicki, Rafal
Bielicki, Grzegorz
Berezowski, Mikolaj
Przybylski, Roman
Obremska, Marta
Lukaszewski, Marceli
Larysz, Anna
Kansy, Andrzej
Deja, Marek A
Bicuspid aortic valve repair: outcomes after 17 years of experience
title Bicuspid aortic valve repair: outcomes after 17 years of experience
title_full Bicuspid aortic valve repair: outcomes after 17 years of experience
title_fullStr Bicuspid aortic valve repair: outcomes after 17 years of experience
title_full_unstemmed Bicuspid aortic valve repair: outcomes after 17 years of experience
title_short Bicuspid aortic valve repair: outcomes after 17 years of experience
title_sort bicuspid aortic valve repair: outcomes after 17 years of experience
topic Conventional Aortic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603241/
https://www.ncbi.nlm.nih.gov/pubmed/33889957
http://dx.doi.org/10.1093/ejcts/ezab176
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