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Bicuspid aortic valve repair: outcomes after 17 years of experience
: OBJECTIVES: This study presents the results of 17 years of experience with bicuspid aortic valve (BAV) repair and the analysis of factors associated with repair failure and early echocardiographic outcome. METHODS: Between 2003 and 2020, a total of 206 patients [mean age: 44.5 ± 15.2 years; 152 m...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603241/ https://www.ncbi.nlm.nih.gov/pubmed/33889957 http://dx.doi.org/10.1093/ejcts/ezab176 |
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author | Jasinski, Marek J Kosiorowska, Kinga Gocol, Radoslaw Jasinski, Jakub Nowicki, Rafal Bielicki, Grzegorz Berezowski, Mikolaj Przybylski, Roman Obremska, Marta Lukaszewski, Marceli Larysz, Anna Kansy, Andrzej Deja, Marek A |
author_facet | Jasinski, Marek J Kosiorowska, Kinga Gocol, Radoslaw Jasinski, Jakub Nowicki, Rafal Bielicki, Grzegorz Berezowski, Mikolaj Przybylski, Roman Obremska, Marta Lukaszewski, Marceli Larysz, Anna Kansy, Andrzej Deja, Marek A |
author_sort | Jasinski, Marek J |
collection | PubMed |
description | : OBJECTIVES: This study presents the results of 17 years of experience with bicuspid aortic valve (BAV) repair and the analysis of factors associated with repair failure and early echocardiographic outcome. METHODS: Between 2003 and 2020, a total of 206 patients [mean age: 44.5 ± 15.2 years; 152 males (74%)] with BAV insufficiency with or without aortic dilatation underwent elective aortic valve repair performed by a single surgeon with a mean follow-up of 5 ± 3.5 years. The transthoracic echocardiography examinations were reported. RESULTS: There were no deaths during the hospital stay, and all but 1 patient survived the follow-up period (99.5%). Overall, 10 patients (5%) developed severe insufficiency and 2 (1%) developed aortic dilatation requiring reoperation. Freedom from reoperation at 7 years reached 91.8%. Type 2 BAV configuration [hazard ratio (HR) 3.9; 95% confidence interval (CI): 1.01–60; P = 0.049], no sinotubular junction remodelling (HR 7; 95% CI: 1.7–23; P = 0.005), no circumferential annuloplasty (HR 3.9; 95% CI: 1.01–64; P = 0.047) and leaflet resection (HR 5.7; 95% CI 1.2–13. P = 0.017) have been identified as a risk factor of redo operation. Parameters of the postoperative left ventricle reverse remodelling improved significantly early after the operation and later at 2 years evaluation. CONCLUSIONS: The repair of BAV offers good short- and mid-term results providing a significant reverse left ventricular remodelling. Type 0 BAV preoperative configuration, circumferential annuloplasty and sinotubular junction remodelling are associated with better repair durability. |
format | Online Article Text |
id | pubmed-8603241 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-86032412021-11-22 Bicuspid aortic valve repair: outcomes after 17 years of experience Jasinski, Marek J Kosiorowska, Kinga Gocol, Radoslaw Jasinski, Jakub Nowicki, Rafal Bielicki, Grzegorz Berezowski, Mikolaj Przybylski, Roman Obremska, Marta Lukaszewski, Marceli Larysz, Anna Kansy, Andrzej Deja, Marek A Eur J Cardiothorac Surg Conventional Aortic Surgery : OBJECTIVES: This study presents the results of 17 years of experience with bicuspid aortic valve (BAV) repair and the analysis of factors associated with repair failure and early echocardiographic outcome. METHODS: Between 2003 and 2020, a total of 206 patients [mean age: 44.5 ± 15.2 years; 152 males (74%)] with BAV insufficiency with or without aortic dilatation underwent elective aortic valve repair performed by a single surgeon with a mean follow-up of 5 ± 3.5 years. The transthoracic echocardiography examinations were reported. RESULTS: There were no deaths during the hospital stay, and all but 1 patient survived the follow-up period (99.5%). Overall, 10 patients (5%) developed severe insufficiency and 2 (1%) developed aortic dilatation requiring reoperation. Freedom from reoperation at 7 years reached 91.8%. Type 2 BAV configuration [hazard ratio (HR) 3.9; 95% confidence interval (CI): 1.01–60; P = 0.049], no sinotubular junction remodelling (HR 7; 95% CI: 1.7–23; P = 0.005), no circumferential annuloplasty (HR 3.9; 95% CI: 1.01–64; P = 0.047) and leaflet resection (HR 5.7; 95% CI 1.2–13. P = 0.017) have been identified as a risk factor of redo operation. Parameters of the postoperative left ventricle reverse remodelling improved significantly early after the operation and later at 2 years evaluation. CONCLUSIONS: The repair of BAV offers good short- and mid-term results providing a significant reverse left ventricular remodelling. Type 0 BAV preoperative configuration, circumferential annuloplasty and sinotubular junction remodelling are associated with better repair durability. Oxford University Press 2021-04-23 /pmc/articles/PMC8603241/ /pubmed/33889957 http://dx.doi.org/10.1093/ejcts/ezab176 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Conventional Aortic Surgery Jasinski, Marek J Kosiorowska, Kinga Gocol, Radoslaw Jasinski, Jakub Nowicki, Rafal Bielicki, Grzegorz Berezowski, Mikolaj Przybylski, Roman Obremska, Marta Lukaszewski, Marceli Larysz, Anna Kansy, Andrzej Deja, Marek A Bicuspid aortic valve repair: outcomes after 17 years of experience |
title | Bicuspid aortic valve repair: outcomes after 17 years of experience |
title_full | Bicuspid aortic valve repair: outcomes after 17 years of experience |
title_fullStr | Bicuspid aortic valve repair: outcomes after 17 years of experience |
title_full_unstemmed | Bicuspid aortic valve repair: outcomes after 17 years of experience |
title_short | Bicuspid aortic valve repair: outcomes after 17 years of experience |
title_sort | bicuspid aortic valve repair: outcomes after 17 years of experience |
topic | Conventional Aortic Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603241/ https://www.ncbi.nlm.nih.gov/pubmed/33889957 http://dx.doi.org/10.1093/ejcts/ezab176 |
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