Preclinical testing of chimeric antigen receptor T cells in neuroblastoma mouse models

The translation of chimeric antigen receptor (CAR) T cell therapy for pediatric solid tumors is limited by the lack of preclinical models that fully recapitulate solid tumor biology. We describe steps to implement neuroblastoma metastatic and orthotopic mouse models. We delineate an analysis pipelin...

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Detalles Bibliográficos
Autores principales: Li, Nan, Nguyen, Rosa, Thiele, Carol J., Ho, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603305/
https://www.ncbi.nlm.nih.gov/pubmed/34825213
http://dx.doi.org/10.1016/j.xpro.2021.100942

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