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Genetic mosaic dissection of candidate genes in mice using mosaic analysis with double markers
Mosaic analysis with double markers (MADM) technology enables the generation of genetic mosaic tissue in mice. MADM enables concomitant fluorescent cell labeling and introduction of a mutation of a gene of interest with single-cell resolution. This protocol highlights major steps for the generation...
Autores principales: | Amberg, Nicole, Hippenmeyer, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603308/ https://www.ncbi.nlm.nih.gov/pubmed/34825212 http://dx.doi.org/10.1016/j.xpro.2021.100939 |
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