A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN

[Image: see text] Dendritic cells (DC) are antigen-presenting cells coordinating the interplay of the innate and the adaptive immune response. The endocytic C-type lectin receptors DC-SIGN and Langerin display expression profiles restricted to distinct DC subtypes and have emerged as prime targets f...

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Detalles Bibliográficos
Autores principales: Wawrzinek, Robert, Wamhoff, Eike-Christian, Lefebre, Jonathan, Rentzsch, Mareike, Bachem, Gunnar, Domeniconi, Gary, Schulze, Jessica, Fuchsberger, Felix F., Zhang, Hengxi, Modenutti, Carlos, Schnirch, Lennart, Marti, Marcelo A., Schwardt, Oliver, Bräutigam, Maria, Guberman, Mónica, Hauck, Dirk, Seeberger, Peter H., Seitz, Oliver, Titz, Alexander, Ernst, Beat, Rademacher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603350/
https://www.ncbi.nlm.nih.gov/pubmed/34748320
http://dx.doi.org/10.1021/jacs.1c07235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603350/
https://www.ncbi.nlm.nih.gov/pubmed/34748320
http://dx.doi.org/10.1021/jacs.1c07235

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