Cargando…
Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice
[Image: see text] Opioid use disorders and fatal overdose due to consumption of fentanyl-laced heroin remain a major public health menace in the United States. Vaccination may serve as a promising potential remedy to combat accidental overdose and to mitigate the abuse potential of opioids. We previ...
Autores principales: | Barrientos, Rodell C., Whalen, Connor, Torres, Oscar B., Sulima, Agnieszka, Bow, Eric W., Komla, Essie, Beck, Zoltan, Jacobson, Arthur E., Rice, Kenner C., Matyas, Gary R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603354/ https://www.ncbi.nlm.nih.gov/pubmed/34076427 http://dx.doi.org/10.1021/acs.bioconjchem.1c00179 |
Ejemplares similares
-
Novel Vaccine That Blunts Fentanyl Effects and Sequesters
Ultrapotent Fentanyl Analogues
por: Barrientos, Rodell C., et al.
Publicado: (2020) -
Novel chimeric monoclonal antibodies that block fentanyl effects and alter fentanyl biodistribution in mice
por: Ban, Bhupal, et al.
Publicado: (2021) -
Effect of Preexisting Immunity to Tetanus Toxoid on the Efficacy of Tetanus Toxoid-Conjugated Heroin Vaccine in Mice
por: Komla, Essie, et al.
Publicado: (2021) -
Synthesis and immunological effects of C14-linked 4,5-epoxymorphinan analogues as novel heroin vaccine haptens
por: Gutman, Eugene S., et al.
Publicado: (2021) -
Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines
por: Sulima, Agnieszka, et al.
Publicado: (2022)